+ More Filters

Reset Filters

Title

Funding Organization

Funding Type

Eligible Country

Deadline

Other (Select all that apply)

Show Expired Programs

Show Verified Programs

Not Verified

Innovation Grant in Alex's Lemonade Stand Foundation

Alex's Lemonade Stand Foundation

ALSF is committed to creating opportunities for new and innovative research into treatments and cures for childhood cancers. The Innovation Grant is designed to provide critical and significant seed funding for established researchers with a novel approach to pediatric oncology scientific investigation. Proposals should have clinical translation in view. This may represent a change in research direction and/or an innovative new idea that moves away from an investigator’s prior research but for which a strong case is made for the potential impact on childhood cancers.

Application Timeline and Review
•
A letter of intent (LOI) must be submitted, and all eligibility criteria met to be considered for the full proposal stage; otherwise, LOIs will be administratively rejected.
•
Upon invitation a full proposal must be submitted that meets all guideline criteria as well as all eligibility criteria; otherwise, applications will be administratively rejected.
•
LOIs and full proposals will be reviewed by an independent panel of experts according to the NIH recognized peer-review process.
APPLICATION TIMELINE
LETTER OF INTENT DUE OCTOBER 15, 2025 BY 8:00 P.M. ET
INVITATION TO SUBMIT FULL PROPOSAL
JANUARY 15, 2026

FULL PROPOSAL DUE MARCH 18, 2026 by 8:00 p.m. ET
NOTIFICATION
JULY 2026

Scope of Proposal
•
Proposals must fall within the scope of Alex’s Lemonade Stand Foundation’s mission, focused on childhood cancers. Proposals with a sole/primary focus on patients >19 years of age will not be considered.
•
Proposal must be hypothesis driven and mechanistic.
•
Innovation must be clearly presented.
•
Potential for major scientific and/or clinical impact in pediatric oncology is critical.
•
While preliminary data are not required, the applicant must demonstrate feasibility of the research plan.

Budget
The requested budget should be in proportion to the scope of the proposed project and should be for direct costs of $250,000 USD or below over two years. A maximum of $125,000 in total direct costs may be requested per year.

AI Based Application Success Predictor

1. 🎯 Strong Alignment with ALSF’s Mission & Research Focus

ALSF funds research specifically in childhood cancer — proposals must clearly focus on cancers in children (not adult cancers), and especially on novel approaches, new therapies, or filling critical gaps in pediatric oncology. alexslemonade.org+2alexslemonade.org+2

Projects should aim toward less toxic treatments, improved survivorship, or therapies for cancers that are currently hard to treat. alexslemonade.org+1

2. 🧑‍🔬 Appropriate Career Stage & Grant Program

ALSF offers different award types depending on career stage: e.g., the “A” Award (up to ~US $800,000/4 years) for early faculty establishing independence. Research at UCalgary+1

They expect applicants to have a clear commitment to pediatric cancer research — for example, you should demonstrate that this field will be your long-term focus. Research at UCalgary+1

3. 📚 Innovation, Novelty & Feasibility

ALSF explicitly states that they want projects that are original and not currently being funded. For example, the “A” Award guidelines say: “original project that is not currently being funded.” Research at UCalgary

Feasibility matters: strong scientific rationale, well-designed research plan, realistic budget, and milestones.

4. 🏫 Institutional Support & Protected Research Time

For major awards (e.g., “A” Award), applicants must allocate a large percentage of their time (e.g., ≥ 75%) to research activities during the grant period. Research at UCalgary

Institutional commitment (department chairs, division chiefs) and letters of support strengthen applications.

5. 🔄 Resource Sharing & Broader Impact

ALSF requires applicants to include a Resource Sharing Plan: if you generate unique reagents, data, or tools, you must describe how those will be shared. Research at UCalgary

They value the long-term impact of the research — e.g., whether it can lead to trials, new therapies, or make a meaningful difference in childhood cancer outcomes. alexslemonade.org+1

6. 🤝 Collaboration & Big Picture Thinking

Some ALSF initiative programs (e.g., the “Crazy 8 Initiative”) fund large, multi-investigator, multi-institution teams tackling the most difficult childhood cancers. These projects are collaborative, high-risk/high-reward. alexslemonade.org+1

Even for smaller grants, showing connections, cross-discipline thinking, or potential for follow-on funding is beneficial.

📋 Summary Table of Success Predictors

Success Predictor	Why It Matters for ALSF Applications
Clear focus on childhood cancer	Funders only consider pediatric cancers (not adult cancers)
Appropriate award match (career stage, scope)	Ensures you fit the eligibility and expectations of the award
Novel, not-currently-funded project idea	Demonstrates uniqueness and ability to fill a gap
Strong scientific design, feasibility & milestones	Shows you can execute and deliver meaningful results
Institutional backing & protected time	Funders want to know you have support and time to succeed
Resource-sharing plan and broader impact	Amplifies value of investment and aligns with ALSF ethos
Collaboration or long-term translational potential	Strengthens potential for major impact and follow-on opportunities

Specialties

Cancer

Eligibility Requirements

•
Applicant institutions must be based in the United States or Canada. Applicants need not be United States citizens. Funds must be granted to nonprofit institutions or organizations.
•
Applicants must have an MD, PhD, or MD/PhD (or equivalent) and be appointed as faculty (or equivalent) at an academic institution.
•
Applicants must have a track record of publication with at least one publication as a Senior Corresponding Author and funding productivity that demonstrates the project can be accomplished by the investigators.
•
Applicants must have a track record of research grant productivity with at least one NIH R01 equivalent awarded. Please read the ALSF R01 equivalency policy for more details.
•
Applicant must propose a new research direction, not a continuation of ongoing funded research.

Sponsor Details

Sponsor Institute/Organizations: Alex's Lemonade Stand Foundation

Sponsor Type: Corporate/Non-Profit

Address: 333 E. Lancaster Ave, #414, Wynnewood, PA 19096 USA Phone: 866.333.1213

Legal & Affiliation Disclaimer

Affiliation Disclaimer: Trialect operates independently and is not affiliated with, endorsed by, or supported by any sponsors or organizations posting on the GrantsBoard platform. As an independent aggregator of publicly available funding opportunities, Trialect provides equal access to information for all users without endorsing any specific funding source, content, organization, or sponsor. Trialect assumes no responsibility for the content posted by sponsors or third parties.

Subscription Disclaimer: Upon logging into Trialect, you may choose to SUBSCRIBE to GrantsBoard for timely notifications of funding opportunities and to access exclusive benefits, such as priority alerts, reminders, personalized recommendations, and additional application support. However, users are advised to contact sponsors directly for any questions and are not required to subscribe to engage with funding opportunities.

Content Ownership and Copyright Disclaimer: Trialect respects the intellectual property rights of all organizations and individuals. All content posted on GrantsBoard is provided solely for informational purposes and remains the property of the original owners. Trialect does not claim ownership of, nor does it have any proprietary interest in, content provided by third-party sponsors. Users are encouraged to verify content and ownership directly with the posting sponsor.

Fair Use Disclaimer: The information and content available on GrantsBoard are compiled from publicly accessible sources in alignment with fair use principles under U.S. copyright law. Trialect serves as an aggregator of this content, offering it to users in good faith and with the understanding that it is available for public dissemination. Any organization or individual who believes their intellectual property rights have been violated is encouraged to contact us for prompt resolution.

Third-Party Posting Responsibility Disclaimer: Trialect is a neutral platform that allows third-party sponsors to post funding opportunities for informational purposes only. Sponsors are solely responsible for ensuring that their postings comply with copyright, trademark, and other intellectual property laws. Trialect assumes no liability for any copyright or intellectual property infringements in third-party content and will take appropriate action to address any substantiated claims.

Accuracy and Verification Disclaimer: Trialect makes no warranties regarding the accuracy, completeness, or reliability of the information provided by sponsors. Users are advised to verify the details of any funding opportunity directly with the sponsor before taking action. Trialect cannot be held liable for any discrepancies, omissions, or inaccuracies in third-party postings.

Notice and Takedown Policy: Trialect is committed to upholding copyright law and protecting the rights of intellectual property owners. If you believe that content on GrantsBoard infringes your copyright or intellectual property rights, please contact us with detailed information about the claim. Upon receipt of a valid notice, Trialect will promptly investigate and, where appropriate, remove or disable access to the infringing content.

View Funding Opportunity