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Clinical Cancer Research Program

Rising Tide Foundation

Rising Tide Foundation for Clinical Cancer Research (RTFCCR) supports innovative and unique patientcentered clinical trials with the potential to impact the lives of cancer patients timely. Our overall goal is to improve cancer patients' treatment options and quality of life by funding clinical studies focused on therapy optimization, disease and treatment burden, and early detection and intervention. We fund phase I to phase III interventional clinical trials. Please note we do not support basic research, observational or epidemiological studies, or trials that could generate revenue for start-ups or pharmaceutical companies.

Maximum award and duration

Please be aware that RTFCCR does not cover the full clinical trial cost. RTFCCR normally funds USD 100,000 per each year of the trial duration. Awarded funds will be paid on a milestone-driven basis. Funds should be used for non-reimbursable approved treatment and study-related patient-care costs, including patient participation costs such as travel and parking, extraordinary translational and imaging studies, and supplies. Funds may also be used to support the salary of the principal investigator, patient partner, and other key personnel. Equipment costs will be funded only if use is demonstrated to be entirely related to the project financed by RTFCCR.

A grant usually lasts up to five years. RTFCCR will disburse the funds only if the recipient follows reporting and participating in accrual requirements outlined in the grant agreement.

AI Based Application Success Predictor

From a reviewer’s perspective, strong Rising Tide clinical research proposals generally exhibit:

✔ Clear Patient-Centric Impact

Projects must articulate how outcomes will tangibly improve patient outcomes or care within a few years. Rising Tide Foundation

✔ Scientific Rigor & Innovation

Proposals should include robust methodology, clear hypotheses, and appropriate trial design or intervention mechanisms. Rising Tide Foundation

✔ Active Patient Involvement

Meaningful inclusion of patient partners in study design, conduct, and dissemination is essential and often required. Rising Tide Foundation

✔ Feasibility & Milestone Planning

Realistic budgets, timelines with clear milestones, and evidence of institutional and co-funding support strengthen competitiveness. Rising Tide Foundation

✔ Scalability & Equity

Especially for ACCESS and supportive care awards, proposals with scalable, low-cost interventions and equity reach (e.g., LMIC applicability) are favoured. Rising Tide Foundation

🛠 Practical Tips for Applicants

✔ Submit a concise LOI: Early screening reduces time to invitation for full proposals. Rising Tide Foundation
✔ Integrate patients from day one: Early and meaningful patient engagement should be embedded and funded. Rising Tide Foundation
✔ Demonstrate co-funding: For larger awards, show confirmed or planned co-financial support. Rising Tide Foundation
✔ Align with strategic focus: Include therapy optimization, early detection/ intervention, or disease burden mitigation. Rising Tide Foundation
✔ Plan for data and outcomes: Lay out clinical endpoints and measurable impact within 3–5 years. Rising Tide Foundation

📌 Summary: Rising Tide Foundation Funding

Programme	Focus	Key Features	Funding Example
RTFCCR Clinical Grants	Interventional clinical cancer research	Patient partners; impact within years	Variable tailored funding Rising Tide Foundation
ACCESS Award	Scalable, equitable cancer solutions	50% co-funding required	Up to $500,000 Rising Tide Foundation
Early Career Supportive Care	Supportive care clinical trials	Early career + mentorship	~$245,000/4 yrs Rising Tide Foundation
Pre-application Grants	Patient partner early engagement	Small gap-funding	~$1,000–$3,000 Rising Tide Foundation

🔍 When Rising Tide Funding Is a Good Fit

✔ You are an independent clinical investigator planning an interventional cancer trial with clear patient impact. Oncodaily
✔ Your research application includes patient partners and measurable outcomes. Rising Tide Foundation
✔ You seek scalable solutions that can impact clinical practice or equity globally. Rising Tide Foundation
✔ You are an early career investigator focusing on supportive care with a mentor.

Specialties

Cancer

Clinical Trials

Eligibility Requirements

Applicants must hold a doctoral degree and have a faculty appointment (or equivalent) with an academic institution, including research institutions that are not formally associated with a university, at the time of the award term. Both early-career and established investigators are encouraged to apply.

An applicant must be an independent investigator with demonstrated experience and training to be able to organize, manage, and implement the clinical trial to meet milestones and timelines, and to protect the rights and welfare of the human subject participant.

The application must convey the institution's commitment to both the applicant and the proposed research activities. RTFCCR does not have any geographical or cancer type restrictions. International teams are welcome. Typically, a grantee can only have one active grant at a time.

To be eligible for funding, proposed clinical trials must meet the following criteria:

- Clinical trials must be interventional, early to late stage (Phase 1, 2, and 3); they may include secondary non-clinical endpoints.

- Applications must have patient partner involvement (see the section “Patient partner involvement in research” on page 6 for more information). If this is not the case, you can apply for a pre-application grant. Please find more information here (Pre-application Grants - Rising Tide Foundation).

- The application must be submitted in English.

Sponsor Details

Sponsor Institute/Organizations: Rising Tide Foundation

Sponsor Type: Corporate/Non-Profit

Address: Herrenacker 15 8200 Schaffhausen

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