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Accelerator Grants: Migraine Research

Brain Canada

The Accelerator Grants: Migraine Research program aims to support bold, innovative research that has the potential to drive new insights and improve prevention, diagnosis, and treatment strategies for migraine.

The program will support research that advances our understanding of the causes, risk factors, and symptoms of migraine, including, but not limited to, the biological underpinnings of the condition; the identification of biomarkers to enhance prevention, diagnosis, and treatment management; and the development and testing of novel therapies or interventions. Projects must consider the influence of sexand gender-related factors in the design, analysis, and evaluation of the research given the disproportionate impact of migraine on women.

It is anticipated that this funding will catalyze new insights and support the generation of preliminary data, tools, or interventions that can inform and enable new directions in the field.

Grant Details

The Accelerator Grants: Migraine Research program has an overall funding envelope of $480,000 CAD to support up to three grants of $160,000 each over three years. Grants are non-renewable.

Equity, Diversity, and Inclusion

Evidence clearly shows that increasing equity, diversity and inclusion in research environments enhances excellence, innovation and creativity. We are committed to excellence through equity and encourage applicants of diverse backgrounds to apply to our funding opportunities, which will promote the expression of diverse perspectives, approaches, and experiences, including those of underrepresented groups.

Use of Funds Funds must contribute toward the direct costs of the research project for which they were awarded and should be directly attributable to the project or activity being performed. Funds can only be disbursed and used within Canada. Exceptions may be considered on a case-by-case basis with clear justification and prior approval from Brain Canada.

AI Based Application Success Predictor

1. Strong neuroscience relevance

The most competitive applications directly address:

neurodegenerative disease,
mental health,
brain injury,
neurodevelopment,
neuroimmunology,
neural circuitry,
brain imaging,
cognitive neuroscience,
neurotechnology,
brain disorders.

Projects clearly advancing brain science are strongly favored.

2. Transformative and innovative science

Brain Canada strongly prioritizes:

high-risk/high-reward ideas,
breakthrough neuroscience,
novel neurotechnologies,
innovative translational approaches,
interdisciplinary brain research.

Innovation is one of the strongest predictors of competitiveness.

3. Strong translational or clinical impact

Successful proposals often demonstrate potential to:

improve diagnosis,
develop therapies,
advance brain-health interventions,
improve neurological outcomes,
support precision neuroscience,
influence patient care.

Applications connecting discovery science with patient benefit tend to perform especially well.

4. Interdisciplinary collaboration

High-scoring projects frequently involve:

neuroscientists,
neurologists,
psychiatrists,
engineers,
AI/data scientists,
rehabilitation specialists,
geneticists,
computational biologists.

Cross-disciplinary integration is heavily valued.

5. Strong methodological rigor

Competitive proposals generally demonstrate:

robust experimental design,
validated models,
advanced analytics,
reproducibility,
realistic milestones,
strong statistical planning.

Weak methodology is a major reviewer concern.

6. Strong preliminary data

Applications with:

pilot neuroscience findings,
proof-of-concept neurotechnology,
preliminary imaging/genomic data,
translational feasibility evidence,
prior publications

typically receive stronger reviewer confidence.

7. Team science and collaborative networks

Brain Canada strongly favors:

multi-institutional collaborations,
national neuroscience networks,
integrated translational platforms,
shared infrastructure models,
collaborative data ecosystems.

Large collaborative ecosystems are highly competitive.

8. Equity, diversity, and inclusion (EDI)

Brain Canada increasingly prioritizes:

inclusive research participation,
diversity in neuroscience training,
equitable patient representation,
Indigenous health engagement,
accessibility in research design.

Meaningful EDI integration strengthens applications.

9. Strong investigator track record

Important predictors include:

impactful neuroscience publications,
prior grant success,
international collaborations,
leadership in neuroscience initiatives,
translational research productivity.

For early-career programs, trajectory and future potential are heavily considered.

10. Potential for long-term impact and scalability

Reviewers favor projects likely to:

generate major CIHR/international funding,
support commercialization,
influence brain-health policy,
establish new neuroscience platforms,
create scalable technologies or therapies.

Specialties

Cancer

Eligibility Requirements

This opportunity supports multidisciplinary teams that bring together the expertise required to address this complex neurological condition. Where appropriate, applicants are encouraged to meaningfully engage people with lived experience to ensure that research priorities, design, and outcomes reflect realworld needs and perspectives.

• Teams must include a minimum of two independent investigators, as described below, with one designated as the Principal Investigator.

• Investigators must be conducting research at, and affiliated with, an eligible Canadian academic institution for the entire duration of the grant and must be considered a full-time independent researcher at their institution. Such an individual normally holds the rank of assistant, associate, or full professor; can initiate and direct their own independent lines of research as principal investigator; has full responsibility for running their laboratories; has full control of their research funds; and is permitted to supervise trainees, if applicable, as per their institution’s policy. Academic appointments must have started by the deadline for Full Application submission. Postdoctoral fellows, research associates, and adjunct faculty are not eligible to apply.

• Teams may include additional members and collaborators, as needed, to ensure the required expertise is present to carry out the proposed research.

• Proposals may be related but cannot be identical to any other funded projects. It is the responsibility of the applicants to notify Brain Canada immediately should overlap arise from funding awarded during the application and review process of this funding opportunity. Overlap is defined as having the same objectives and/or experimental aims as any other funded work.

• Applicants can only submit one application as Principal Investigator.

• Applicants must submit a Registration Form to be eligible to submit a Full Application.

• Applicants must be able to initiate the project in February 2027, when funding is expected to begin.

Sponsor Details

Sponsor Institute/Organizations: Brain Canada

Sponsor Type: Corporate/Non-Profit

Address: 1200 McGill College Avenue Suite 1600, Montreal, Quebec H3B 4G7

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