+ More Filters

Reset Filters

Title

Funding Organization

Funding Type

Eligible Country

Deadline

Other (Select all that apply)

Show Expired Programs

Show Verified Programs

Verified

‘A’ Award Grant

Alex's Lemonade Stand Foundation

The purpose of the ‘A’ Award Grant is to advance ALSF’s mission to find cures and better treatments for childhood cancers by providing support to early career scientists who want to establish a career in pediatric oncology research. The ideal applicant has an original project that is not currently being funded. Demonstration of a future commitment to pediatric cancer investigation as well as institutional support for the career development of the investigator are critical components of a successful application. A mentor is required, and a career development plan must be included.

Application Timeline and Review

• A full proposal must be submitted that meets all guideline criteria as well as all eligibility criteria; otherwise, applications will be administratively rejected.

• Proposals will be reviewed by an independent panel of experts according to the NIH recognized peer-review process.

Scope of Proposal

• Proposals must fall within the scope of Alex’s Lemonade Stand Foundation’s mission, focused on childhood cancers. Proposals with a sole/primary focus on patients >19 years of age will not be considered.

Budget

The requested budget should be in proportion to the scope of the proposed project and should be at or under $800,000 USD in direct costs over four years. A maximum of $200,000 in total costs may be requested per year.

AI Based Application Success Predictor

🧒 1. Strong Focus on Pediatric Cancer (Non-Negotiable)

Proposals must directly address:
- Childhood cancers (not adult oncology)
Priority areas:
- High-risk, relapsed, or rare pediatric cancers

👉 ALSF funds projects that fill critical gaps in pediatric oncology

🔬 2. High Scientific Excellence (Top Predictor)

Grants are selected via rigorous peer review (NIH-style)
Key evaluation factors:
- Scientific significance
- Innovation
- Impact

👉 Funding is awarded primarily based on peer-review ranking and quality of science

🚀 3. Innovation & Novel Ideas (Critical)

ALSF strongly favors:
- New, original, and high-risk ideas
Especially projects:
- Not yet funded elsewhere
- Lacking preliminary data but highly promising

👉 Foundation explicitly supports early-stage, innovative concepts

🔄 4. Translational Potential (Bench → Bedside)

Strong preference for:
- Research that can move toward clinical application
Example:
- Reach Grants aim to push research toward clinical trials

👉 Projects must show a clear path to patient benefit

🎯 5. Addressing Unmet Clinical Needs

Successful proposals:

Target cancers with:
- Poor outcomes
- Limited treatment options
Aim to:
- Develop new therapies
- Improve survival or reduce toxicity

👉 “Unmet need” is a major decision factor

👩‍🔬 6. Investigator Potential & Career Development

ALSF strongly invests in researchers:

Early-career:

Commitment to pediatric oncology
Strong mentorship + career plan

Senior investigators:

Track record + leadership

👉 Many grants are designed to build future pediatric cancer leaders

🧪 7. Feasible, Well-Designed Study

Clear:
- Hypothesis
- Methodology
- Timeline
Realistic scope aligned with funding

👉 Feasibility is essential due to competitive funding environment

🤝 8. Collaboration & Multidisciplinary Teams

Strong proposals often include:
- Multi-institution collaborations
- Cross-disciplinary expertise

👉 Large initiatives (e.g., “Crazy 8”) emphasize team science

📊 9. Potential for High Impact & Future Funding

ALSF evaluates whether research will:
- Lead to larger grants (NIH, etc.)
- Produce meaningful scientific or clinical advances

👉 ALSF acts as seed + accelerator funding

🌐 10. Resource Sharing & Broader Impact

Applicants must include:
- Plans to share data, tools, or reagents
Emphasis on:
- Advancing the broader research community

📊 Summary: Key Predictors (Ranked)

Highest impact factors:

Pediatric cancer focus
Scientific excellence
Innovation

Moderate predictors:
4. Translational potential
5. Addressing unmet clinical needs
6. Investigator potential

Supporting factors:
7. Feasibility
8. Collaboration
9. Future funding potential

💡 Insider Insight

Compared to other pediatric cancer funders:

Alex's Lemonade Stand Foundation is:
👉 innovation-driven + gap-filling

👉 Key success question:
“Is this a bold, high-quality idea that could lead to a cure for childhood cancer—and isn’t already funded elsewhere?”

High-risk ideas ✔️
Pediatric focus ✔️
Clear path to impact ✔️
→ Highest success probability

Specialties

Cancer

Oncology

Clinical Trials

Eligibility Requirements

• Applicant institutions must be based in the United States or Canada. Applicants need not be United States citizens. Funds must be granted to nonprofit institutions or organizations.

• Applicants must have an MD, PhD or MD/PhD (DO, MBBS or equivalent) and be within five years of their first faculty appointment as an Assistant Professor at the time that their application is submitted as well as:

o MD and MD/PhD must be within 10 years of their terminal research degree or end of post-graduate clinical training (whichever date is later).

o PhD must be within 10 years of their terminal research degree.

• More senior Assistant Professors, as well as Associate and Full Professors, are ineligible. If still at the Instructor level, the applicant must have a firm commitment from the Department Chair/Division Chief at the time of grant submission for an Assistant Professor position within one year of receiving the award.

• A minimum of 75% of the applicant’s time during the ‘A’ Award period must be allocated as non-clinical protected time for all research activities. This percentage of time includes both ‘A’ Award activities and the applicant’s other research responsibilities.

• Mentor(s) must be identified and must be in the applicant’s home institution. A comentor whose research expertise is aligned with the application could be added from an outside institution.

• Applicants cannot be the Principal Investigator (PI) of a K99/R00 or other independent, nationally competitive award (e.g., R01 or equivalent, P or U award) that has been funded or recommended for funding (i.e., will be funded) any time before the ‘A’ Award grant start date.

o Please review ALSF’s R01 equivalency policy on the grant recipients page of our website. If the applicant has an award not listed on the equivalency policy, contact ALSF at least four weeks before the application due date to determine eligibility.

• Applicants may have mentored-career development grants (such as K01, K08, K23, K25) or mentored-research grants (such as ACS-Clinician Scientist Development Grant; DoD Physician Research Award) from other funding sources before or during the ‘A’ Award period, but there must be clear documentation of how scientific and budgetary overlap will be avoided.

• Applicants currently holding an ALSF Young Investigator (YI) Grant may apply. If the ‘A’ Award is given, it would supersede the YI grant if there is an overlap in the funding periods.

Sponsor Details

Sponsor Institute/Organizations: Alex's Lemonade Stand Foundation

Sponsor Type: Corporate/Non-Profit

Address: 333 E. Lancaster Ave, #414, Wynnewood, PA 19096

Legal & Affiliation Disclaimer

Affiliation Disclaimer: Trialect operates independently and is not affiliated with, endorsed by, or supported by any sponsors or organizations posting on the GrantsBoard platform. As an independent aggregator of publicly available funding opportunities, Trialect provides equal access to information for all users without endorsing any specific funding source, content, organization, or sponsor. Trialect assumes no responsibility for the content posted by sponsors or third parties.

Subscription Disclaimer: Upon logging into Trialect, you may choose to SUBSCRIBE to GrantsBoard for timely notifications of funding opportunities and to access exclusive benefits, such as priority alerts, reminders, personalized recommendations, and additional application support. However, users are advised to contact sponsors directly for any questions and are not required to subscribe to engage with funding opportunities.

Content Ownership and Copyright Disclaimer: Trialect respects the intellectual property rights of all organizations and individuals. All content posted on GrantsBoard is provided solely for informational purposes and remains the property of the original owners. Trialect does not claim ownership of, nor does it have any proprietary interest in, content provided by third-party sponsors. Users are encouraged to verify content and ownership directly with the posting sponsor.

Fair Use Disclaimer: The information and content available on GrantsBoard are compiled from publicly accessible sources in alignment with fair use principles under U.S. copyright law. Trialect serves as an aggregator of this content, offering it to users in good faith and with the understanding that it is available for public dissemination. Any organization or individual who believes their intellectual property rights have been violated is encouraged to contact us for prompt resolution.

Third-Party Posting Responsibility Disclaimer: Trialect is a neutral platform that allows third-party sponsors to post funding opportunities for informational purposes only. Sponsors are solely responsible for ensuring that their postings comply with copyright, trademark, and other intellectual property laws. Trialect assumes no liability for any copyright or intellectual property infringements in third-party content and will take appropriate action to address any substantiated claims.

Accuracy and Verification Disclaimer: Trialect makes no warranties regarding the accuracy, completeness, or reliability of the information provided by sponsors. Users are advised to verify the details of any funding opportunity directly with the sponsor before taking action. Trialect cannot be held liable for any discrepancies, omissions, or inaccuracies in third-party postings.

Notice and Takedown Policy: Trialect is committed to upholding copyright law and protecting the rights of intellectual property owners. If you believe that content on GrantsBoard infringes your copyright or intellectual property rights, please contact us with detailed information about the claim. Upon receipt of a valid notice, Trialect will promptly investigate and, where appropriate, remove or disable access to the infringing content.

View Funding Opportunity