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2023 Rheumatoid Arthritis Research

The Arthritis Foundation

Background

The Arthritis Foundation has previously supported groundbreaking research that led to the development of early biologics used in the treatment of RA. In 2021, the Arthritis Foundation

Medical and Scientific Advisory Committee formed an Expert Working Group of academic and government RA experts to prioritize the unmet medical needs and potential research areas of interest for funding in RA research. Based on their recommendations, the Arthritis Foundation is releasing this RFP, which is open to investigators affiliated with U.S. academic institutions and hospitals that are committed to improving the outcomes of the RA patient community through biomedical (translational, clinical) and/or health outcomes research.

Why Focus on Understanding and Improving Treatment Response in RA?

Patient responses to currently approved therapies vary widely and may change over a person’s lifetime. The reasons for such variation in outcomes are not well understood but are most likely the result of a combination of factors. Recent advances in development of experimental tools and approaches applicable to the study of blood and tissue of RA patients, along with availability of clinical and demographic data linked to biologic data, provide an opportunity to gain novel insights. These insights have the potential to reveal the underlying causes of therapeutic response, non-response, remission and flare, as well as shed light on novel drug targets.

Specialties

Rheumatology

Eligibility Requirements

Eligibility Criteria for Applicants:

All proposed research projects must be led by a Principal Investigator (PI) who holds a doctorate (e.g., PhD, MD, or equivalent degree).
Applicants who hold the rank of full Professor (or equivalent) are excluded from applying for these opportunities.
For Pilot Awards: PIs must hold a full-time faculty/staff appointment up to and including the rank of Associate Professor (or equivalent), be a clinical fellow, or be an experienced postdoctoral fellow at an academic or other nonprofit research institution within the United States. Applicants holding non-tenure track, full-time, independent, faculty-level positions with titles such as Instructor or Assistant Research Professor are eligible to apply.
For Large Awards: PIs must hold a full-time faculty/staff appointment up to and including the rank of Associate Professor (or equivalent). Applicants holding nontenure track, full-time, independent, faculty-level positions with titles such as Instructor or Assistant Research Professor are eligible to apply. Postdoctoral fellows and clinical fellows are not eligible to apply for this award type.
For purposes of this RFP, an experienced postdoctoral fellow is an individual who holds a doctoral degree (PhD, MD, or an equivalent degree), has completed a minimum of two years of full-time postdoctoral research at the time of application, and who is engaged in a temporary period of mentored research for the purpose of acquiring the professional skills needed to pursue a career path of their choosing. Postdoctoral fellows must have at minimum 90% protected research time.
For the purposes of this RFP, clinical fellows are individuals who are in, or have recently completed, subspecialty fellowship training and are working at an eligible institution (see above criteria). The end date of your fellowship must fall between June 30, 2023 – July 1, 2025, and you must have at minimum 75% protected research time.
If previously funded by the Arthritis Foundation, the applicant must be up to date on all reporting requirements.
Individuals currently holding the role of PI on an active RA Research Program award are not eligible to apply.
Multiple applications will be accepted from a single institution, provided that each application has a different applicant PI and represents a distinct hypothesis.

Arthritis Foundation funds are primarily obtained from individual donations. The amount available for scientific awards each year is determined by the success of the fundraising efforts. Funds for awards are also derived from partnerships established by the Arthritis Foundation with other nonprofit and private sector organizations that share common interests. Funds for subsequent years of a project, after the first, even if initially approved, are contingent upon adequate scientific progress and available funds, and are therefore subject to change.

Eligible Countries:

Sponsor Details

Sponsor Institute/Organizations: The Arthritis Foundation

Sponsor Type:

Address: 1355 Peachtree St NE Suite; 600; Atlanta; GA 30309;United States

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