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CARRA-PReS Collaborative Research Award

Childhood Arthritis and Rheumatology Research Alliance

This funding mechanism aims to support collaborative research activities between CARRA and PReS early career investigators. Early career investigators are defined as faculty (not fellows) who have completed their training/education in the past 10 years. This funding mechanism aims to provide seed funding that allows CARRA and PReS investigators to successfully plan and apply for other grants that could support large-scale collaborative research activities. Grant funds may be used to convene meetings, generate preliminary data, and/or support collaborative pilot studies. 

Grant applications should show how the applicants will leverage the infrastructure of CARRA and PReS, address priority research topics for both communities, engage patients, and extend expertise that would otherwise not be possible working with either group alone.

Grant Project Period Length: 2 Years 

Grant Funding Amount: €50,000 EUR or USD equivalent 

Grant Availability: 1 award 

Application Deadline: April 20, 2026 

Project Period Start Date: August, September or October 1, 2026

AI Based Application Success Predictor

1. Strong Fit to Pediatric Rheumatology / Pediatric Rheumatic Diseases

Projects must clearly address a pediatric rheumatic disease (e.g., JIA, systemic lupus in children, juvenile dermatomyositis, uveitis associated with JIA).

Because CARRA is designed around children’s disease, proposals that are largely adult-disease focused or without pediatric relevance are at risk of being scored lower.
Predictor: Your application should explicitly specify a pediatric rheumatology disease or population, and show relevance to children/families.

2. Use or Leverage of CARRA Infrastructure or Collaborative Model

CARRA has a strong emphasis on multi-site, multi-investigator collaborative research and registry/biobank usage. For example: “Supports research that utilizes the CARRA Registry and/or biorepository …” in one of their grant types. rheumresearch.org+1

Using the registry allows for larger, more representative samples in pediatric rheumatology.
Predictor: Proposals that leverage the CARRA registry, network or multi-centre collaborations often do better (feasibility, scale, impact).

3. Appropriate Grant Mechanism for Your Career Stage & Project Scope

CARRA offers a variety of award types: small “Fellows” grants for trainees (~US $25,000 for 1 year) rheumresearch.org; “Small Grant” (~$50K/1 year) rheumresearch.org; “Pilot JIA Translational Research Grant” (~$175K/2 years) rheumresearch.org; “Mentored Career Development Award” (~$375K/3 years) for early investigators. rheumresearch.org

Matching your career level (fellow, early faculty, independent investigator) to the mechanism is critical.
Predictor: Choose the CARRA award that matches your current role, research maturity, and budget needs.

4. Feasibility with Milestones and Realistic Plan

Given the network and multi-site nature of CARRA’s work, reviewers will look for: clear aims, realistic timelines, mechanisms for recruitment/enrolment (especially using the registry), defined endpoints, risk mitigation.

For example, small grants were awarded for retrospective registry cohort studies (see 2019 Childhood Research Grants example). arthritis.org
Predictor: Applications that include a detailed, realistic plan with milestones and show that the project can be completed within the grant period score better.

5. Innovation & Translational Relevance

While feasibility is key, the strongest applications also propose something novel or impactful: e.g., a new biomarker in JIA, translational use of registry data to inform treatment decisions, a pilot multi-centre intervention.

For example, one funded project in 2019: using the CARRA registry to study “biologic discontinuation in systemic JIA and predictors of flare.” arthritis.org
Predictor: Proposals that address an important gap in pediatric rheumatology, promise to influence care, or use new methods are more competitive.

6. Demonstrated Commitment to Pediatric Rheumatology Research Career

Early investigators applying for career-development awards should demonstrate that they are committed to a research career in pediatric rheumatology, have relevant training, and have mentorship/institutional support.

Network models like CARRA emphasise building the pipeline of pediatric rheumatology investigators. The Rheumatologist
Predictor: Showing career trajectory, mentorship, and institutional backing improves success odds.

7. Strong Collaboration & Team Approach

Since CARRA functions via collaborative mechanisms, having co-investigators from different centres, multi-disciplinary teams (clinician, biostatistician, registry specialist) supports credibility.

Multi-site studies align well with their mission to generate generalizable pediatric rheumatology data.
Predictor: A multi‐centre, collaborative team increases competitiveness.

8. Clear Impact on Patients/Families & Child-Centered Outcomes

Because CARRA’s mission emphasises improving outcomes for children and families with rheumatic disease, proposals that articulate patient/family relevance, child‐friendly endpoints, or quality‐of‐life aspects add value.

The 2024 survey via CARRA’s JA INSIGHTS (pain burden in juvenile arthritis) is one example of child-centred research using CARRA infrastructure. BioMed Central
Predictor: Proposals that highlight child/family impact, patient-centred outcomes or real‐world relevance are stronger.

9. Budget and Grant Duration Appropriate for Scope

Respect the stated maximum award amounts and durations in each RFP (e.g., 1-year fellows grant, up to US $25K; small grant 1 year at US $50K; pilot research 2 years at US $175K). rheumresearch.org
Predictor: A budget that is aligned with the grant's allowed maximum, and avoids over‐scope, resonates better.

10. Clear Writing & Logical Structure

As with any competitive grant, clarity, good writing, clear hypotheses, well‐structured aims, and justification of methods matter enormously.
Predictor: Applications that are well‐written, clearly justified, readily understood by reviewers tend to succeed.

🗓 Summary Table of Typical CARRA Grant Types & Key Fit

Grant TypeAudienceKey Success Fit
Fellows Grant (~US $25K/1yr)Trainees/fellowsFeasible pilot, mentorship emphasized
Small Grant (~US $50K/1yr)Early‐stage investigatorSingle centre or registry retrospective study
Pilot JIA Translational Research (~US $175K/2yrs)Early investigators targeting JIAMulti‐centre, translational, registry‐leveraged
Mentored Career Development (~US $375K/3yrs)Early independent investigatorsCareer development plan + pediatric rheumatology focus

🎯 Final Tips for Applicants to CARRA

Engage with the CARRA network early: attend meetings, collaborate with CARRA committees, understand the registry and its strengths.

Leverage the CARRA Registry or biorepository: if feasible, build your project around existing infrastructure.

Design a child‐fibred, pediatric rheumatology project: articulate why children matter and how your research improves pediatric care.

Assemble a strong mentorship and team environment: especially if you are early‐career.

Be realistic: match scope to grant size and duration.

Write clearly: define specific aims, milestones, endpoints; articulate innovation; show plan for next steps and future funding.

• The application must name two co-PIs, one current CARRA member from North America and one current PReS member from outside North America. 

• To be eligible, MD applicants must also be faculty as defined above 

• Applicants must be CARRA or PReS members who are up to date on membership dues and have current and accurate membership information (location, contact information, and membership status).

Sponsor Institute/Organizations: Childhood Arthritis and Rheumatology Research Alliance

Sponsor Type: Corporate/Non-Profit

Address: 1050 Connecticut Avenue, NW, Suite 500 Washington, DC 20036

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Grant, Award

Letter Of Intent Deadline:

Apr 20, 2026

Final Deadline:

Apr 20, 2026

Funding Amount:

$50,000

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