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Online Traineeship in Molecular Genomics and Translational Biomedical Research

Institute for Regional Health Services, University of Southern Denmark

Klaus Brusgaard, PhD, MSc, is a Professor of Regional Research at the University of Southern Denmark and an internationally recognized expert in clinical genetics, genomics, and translational biomedical research. With over three decades of experience spanning academia, clinical laboratories, and industry, he has made significant contributions to genomic diagnostics, endocrine genetics, and rare disease research. He is a certified Clinical Laboratory Specialist (EBMG) and has held senior academic positions across Denmark and Cyprus, alongside founding Amplexa Genetics A/S. Professor Brusgaard has supervised more than 20 PhD candidates and over 40 MSc and undergraduate research projects, reflecting his strong commitment to mentorship and academic development. He serves as editor and reviewer for leading international journals and is actively involved in major national and international research councils and genomic networks. His work bridges advanced sequencing technologies, variant interpretation, and clinical application, with a strong focus on improving patient-centered genomic medicine.

Main Areas of Interest

Genomic and Transcriptomic Analyses: Expertise in short- and long-read sequencing technologies for genomic and circulating nucleic acids (cfDNA/cfRNA), with applications in disease diagnosis and biomarker discovery.

Molecular Techniques: Skilled in a wide range of laboratory approaches including Sanger sequencing, PCR/RT-PCR, droplet digital PCR (ddPCR), and western blotting for gene and protein expression studies.

Bioinformatics and Functional Genomics: Development and application of computational pipelines for variant detection, expression profiling, and modulation studies in in vitro cellular systems.

Clinical and Translational Research: Active research in diabetes and hyperinsulinism, inherited and acquired cancers (including breast, pancreatic, and prostate), dermatology, and hereditary hemorrhagic telangiectasia, with a focus on bridging molecular insights to patient care.

Specialties

Genetics & Genomics

Techniques You Will Learn

Genomic & Transcriptomic Sequencing
Online training in short- and long-read sequencing technologies for genomic DNA and cfDNA/cfRNA analysis, focusing on workflows, data generation, and quality control.

PCR / RT-PCR
Virtual instruction in conventional and real-time PCR, emphasizing assay design, gene expression analysis, and data interpretation using real datasets.

Droplet Digital PCR (ddPCR)
Advanced online training in sensitive nucleic acid quantification, with applications in rare variant detection and biomarker validation.

Sanger Sequencing
Focused training in Sanger sequencing for mutation confirmation, chromatogram interpretation, and clinical validation.

Western Blotting
Conceptual training in protein detection and quantification, covering workflow principles and result interpretation.

Bioinformatics Pipelines
Hands-on online exposure to variant analysis, gene expression profiling, and functional annotation using open-source tools and curated datasets.

In Vitro Cellular Models
Training in experimental design and data interpretation for gene expression studies using cellular systems.

Clinical & Translational Research
Online exposure to study design and translational applications across diabetes, oncology, dermatology, and hereditary vascular disorders.

Modules

Genomic & Transcriptomic Sequencing for Disease Applications

Principles and applications of short- and long-read sequencing for genomic DNA and circulating nucleic acids (cfDNA/cfRNA), with emphasis on workflows, data generation, quality control, and biomarker discovery.

Molecular Techniques for Gene and Protein Expression Analysis

Online training in core molecular methods including PCR/RT-PCR, droplet digital PCR (ddPCR), Sanger sequencing, and western blotting, focusing on assay design, data interpretation, and clinical validation use-cases.

Quantitative and Sensitive Nucleic Acid Detection

Advanced instruction in ddPCR and real-time PCR for rare variant detection, minimal residual disease monitoring, and biomarker validation using real and simulated datasets.Bioinformatics & Functional Genomics

Hands-on online exposure to computational pipelines for variant detection, gene expression profiling, and functional annotation, integrating curated datasets and open-source analytical tools.

In Vitro Cellular Models and Experimental Design

Training in experimental design and data interpretation for gene expression modulation studies using in vitro cellular systems, linking molecular assays to functional outcomes.

Clinical & Translational Research Applications

Online exposure to clinical study design and translational research across diabetes, hyperinsulinism, oncology (breast, pancreatic, prostate), dermatology, and hereditary hemorrhagic telangiectasia, emphasizing bench-to-bedside integration.

Program Fee


Total Number of Modules	6
Time duration of Each module	45 minutes
Total Program Cost	$562.5

Who Can Apply

PhD scholars or postdoctoral researchers in genetics, molecular biology, biotechnology, bioinformatics

Medical graduates

Host Details

Host Name: Klaus Brusgaard

Affiliation: Institute for Regional Health Services, University of Southern Denmark

Address: Institute for Regional Health Services, University of Southern Denmark, Campusvej 55, 5230 Odense, Denmark

Website URL:

Disclaimer:It is mandatory that all applicants carry workplace liability insurance, e.g., https://www.protrip-world-liability.com (Erasmus students use this package and typically costs around 5 € per month - please check) in addition to health insurance when you join any of the onsite Trialect partnered fellowships.

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