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THE TREAT FTD FUND

The Alzheimer's Drug Discovery Foundation

The Treat FTD fund aims to support the development of drugs or devices for FTD disorders while building a better understanding of FTD pathophysiology, biological mechanisms of disease, and analytically and clinically validated biomarkers with a well-defined context-of-use. The fund aims to de-risk clinical development programs by supporting clinical trial readiness activities or early/mid-stage clinical trials with clear go/no-criteria for later stage drug development. Programs will be considered that test novel or repurposed drug candidates or devices in phase 0, 1 or 2 clinical trials for FTD disorders, led by academic researchers or biotechnology companies, worldwide. Both disease-modifying and symptomatic approaches will be considered.

The RFP seeks to support clinical trials incorporating:

biological mechanisms that have a sound scientific rationale for FTD
biomarkers that would permit evaluation of target engagement, downstream pharmacologic effect, and biological effect
trial designs aligned with constraints associated with a rare disease population
clinical outcome measures that could provide a deeper understanding of the drug mechanism and disease progression
therapeutics applicable to sporadic or genetic forms of FTD. Trials of treatments applicable in sporadic FTD are especially encouraged.

Although the strongest proposals will address all thes

Specialties

Neurosciences

Eligibility Requirements

Funding is open to researchers and clinicians worldwide at:

Academic medical centers, universities, or non-profits. Industry partnerships are encouraged.
Biotechnology companies. Existing companies and new startups are both eligible.
NOTE: All funding is provided through mission-related investments that require return on investment based upon scientific and/or business milestones (see Our Research Strategy for more information)

Sponsor Details

Sponsor Institute/Organizations: The Alzheimer's Drug Discovery Foundation

Sponsor Type: Corporate/Non-Profit

Address: 57 West 57th Street, Suite 904 New York, NY 10019

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