Overview
The Taking Flight Award (1.5 years / $125,000) seeks to promote the careers of early-career investigators to allow them to develop an independent research focus.
Budget
Requests may be made for up to $125,000 for eighteen months. Funding requests may include salary support for the PI, technical staff and/or collaborators; supplies, animal costs, publication fees etc.; and travel to an epilepsy-related conference if the PI is presenting his/her CURE Epilepsy-funded research. Funds are not to be used to purchase equipment. Indirect costs are not supported.
Key Activities and Dates
| Activity | Approximate Date |
| Open Call for Letters of Intent | Monday, November 24, 2025 |
| Letter of Intent Deadline | Tuesday, January 6, 2026 |
| Full Proposal Invitations | Tuesday, February 17, 2026 |
| Full Proposal Deadline | Tuesday, March 24, 2026 |
| Anticipated Award Notification | End of July 2026 |
| Anticipated Project Start Date | Tuesday, September 1, 2026 |
Successful CURE Epilepsy proposals share several strengths in reviewers’ evaluations. Key predictors include:
✔ 1. Clear Alignment With Epilepsy Cure Goals
Projects should directly advance understanding of seizure biology, disease modification (not just symptom suppression), prevention mechanisms, or treatment strategies that could lead to a cure. CURE Epilepsy
✔ 2. Innovation & Breakthrough Potential
CURE highly values high-risk, high-reward science — research that challenges current paradigms or explores underinvestigated mechanisms rather than incremental extensions of well-funded areas. CURE Epilepsy
✔ 3. Feasibility & Measurable Outcomes
Given modest award durations and budgets, reviewers look for well-scoped aims, realistic methods, and specific milestones that can be completed within the funded period. CURE Epilepsy
✔ 4. Evidence of Investigator Readiness
For early career awards like the Taking Flight Award, reviewers assess evidence that the applicant is poised to transition to independence, including the strength of the mentorship plan and track record. CURE Epilepsy
✔ 5. Contribution to Future Funding Trajectory
CURE often funds preliminary work likely to generate pilot data that supports larger NIH/NSF/etc. applications. Demonstrating this potential can strengthen competitiveness. International League Against Epilepsy
✔ 6. Stakeholder Relevance & Lay Communication
Because epilepsy affects patients and families, reviewers (including lay members) value clear communication of significance and relevance to the lived experience of epilepsy — especially in disease burden and outcomes. CURE Epilepsy
✔ Start with the mission: Frame the research in the context of disease modification or prevention, not merely controlling seizures. CURE Epilepsy
✔ Follow LOI guidelines closely: LOI quality heavily influences invitations to full proposals. CURE Epilepsy
✔ Emphasize innovation: Highlight novelty and how the project fills gaps in current epilepsy research. CURE Epilepsy
✔ Demonstrate feasibility: Be explicit about timelines, deliverables, and relevant preliminary data where possible. CURE Epilepsy
✔ Engage mentors for early career awards: A strong mentorship statement is essential for Taking Flight Award candidates. CURE Epilepsy
| Program | Target Audience | Focus | Typical Support |
|---|---|---|---|
| Taking Flight Award | Early career/postdoc/faculty | Independence & pilot research | ~$125k / 18 mo CURE Epilepsy |
| CURE Epilepsy Award | Early career to established investigators | Transformative epilepsy research | ~$250k / 2 yrs Funding Opportunities |
| Seed/Exploratory Grants | Broad researchers | Innovative epilepsy science | ~$50k–$250k (varies) International League Against Epilepsy |
You must fall into one of the following categories to be eligible for the Taking Flight Award:
A postdoctoral fellow with a PhD, PsyD, PharmD, or equivalent and a minimum of two years postdoctoral experience at the time of submission. Applicants must submit a letter of support from their direct supervisor/mentor. For applicants with less than three years of post-doctoral experience, this letter must include a statement from the mentor, clearly articulating a plan to guide the applicant through the project, helping them develop an independent research focus, and encouraging them to think independently and strategically.
A researcher with an appointment as an Instructor or Research Assistant Professor who has yet to obtain significant funding (e.g., RO1 grant or equivalent) and has an on-site mentor committed to advising the applicant.
A faculty member at the assistant professor level who is within one year of having been appointed.
Clinician-researchers who are within two years of their faculty appointment.
A clinical fellow who is pursuing a residency in the following areas: neurology, neurosurgery or neurocritical care, and considering an epilepsy-focused fellowship.
International applicants are welcome; you do not have to be a US citizen or working in the US to apply for this award. All materials must be submitted in English.
Sponsor Institute/Organizations: Citizens United for Research in Epilepsy (CURE Epilepsy)
Sponsor Type: Corporate/Non-Profit
Address: PO Box 10572 Chicago, IL, 60610
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Mar 25, 2026
Mar 25, 2026
$125,000
Affiliation: Citizens United for Research in Epilepsy (CURE Epilepsy)
Address: PO Box 10572 Chicago, IL, 60610
Website URL: https://www.cureepilepsy.org/for-researchers/grants-program/#grant_opportunities
Disclaimer:It is mandatory that all applicants carry workplace liability insurance, e.g., https://www.protrip-world-liability.com (Erasmus students use this package and typically costs around 5 € per month - please check) in addition to health insurance when you join any of the onsite Trialect partnered fellowships.