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Quality Improvement Solutions for the Diagnosis and Management of Migraine and Headache Disorders

American Headache Society

Pfizer and the American Headache Society are collaborating to offer a new grant opportunity seeking proposals for quality improvement initiatives that will address quality gaps in headache medicine, with a goal of producing information or tools that can be widely used in the field and lead to measurable improvements in healthcare services for individuals with headache. Projects should also contribute to the core goal of the American Headache Society (AHS) – improving the lives of people impacted by migraine and other headache disorders. Projects should focus on safety, clinical effectiveness, rapidity of diagnosis/proper treatment, efficiency, patient centered care, and/or equity. The program is not intended to support laboratory science or clinical trials. Project proposals should align with the following core focus areas:

• Diagnosis, treatment and management in primary care and non-headache specialty settings for adult populations

• Collect and analyze patient experience data across multiple sites or a broad population

• Innovative solutions for standardized delivery of headache care and exploration of AI applications in primary care and non-headache specialty settings

• Education specific to headache disorders in medical/allied health schools and residency training

This competitive grant program involves a publicly posted Request for Proposal (RFP) that provides detail regarding a specific area of interest, sets timelines for review and approval. The American Headache Society will select the Expert Review Panel (ERP) to make final grant decisions, create a community of practice for the selected Grantees and share existing knowledge and tools. Organizations are invited to submit an application addressing the knowledge gaps as outlined in the specific RFP. For all quality improvement grants, the grant requester (and ultimately the grantee) is responsible for the design, implementation, and conduct of the independent initiative supported by the grant. Pfizer must not be involved in any aspect of project development, nor the conduct or monitoring of the quality improvement program.

About the American Headache Society The American Headache Society strives to improve the lives of people impacted by migraine and other headache disorders. The AHS is a professional society of health care providers dedicated to the study and treatment of headache and face pain. The Society’s objective is to promote the exchange of information and ideas concerning the causes and treatments of headache and related painful disorders. Educating physicians, health professionals, and the public while encouraging scientific research are the primary functions of our Society. Learn more at AmericanHeadacheSociety.org.

About Pfizer

Pfizer supports the global healthcare community’s independent initiatives (e.g., research, quality improvement, or education) to improve patient outcomes in areas of unmet medical need that are aligned with medical and/or scientific strategies.

Geographic Scope United Sates/Canada

Funding Range and Project Length

Individual projects requesting up to $250,000 USD total over 2 years will be considered. Proposals with smaller budgets are also encouraged.

AI based application success predictor

While Pfizer does not publish a universal scoring rubric, successful applications share several common features, based on how competitive RFPs are structured and how selections are typically made:

1) Strong Alignment With the RFP’s Topic + Unmet Need

Pfizer grant RFPs are narrow: they focus on a detailed research or clinical improvement question (e.g., pneumococcal carriage post-vaccine introduction).
➡️ Success predictor: Your proposal must directly address the specific gap and objectives articulated in the RFP.

2) Clear Relevance to Patient Outcomes or Public Health Impact

Pfizer emphasizes improving patient outcomes in areas of unmet medical need.
➡️ Success predictor: Demonstrate how your project will advance clinical understanding, improve care, or support better health outcomes rather than just adding incremental data.

3) Scientific Merit & Feasibility

Reviewers look for proposals that are:

Well-designed with appropriate methods.

Realistic timelines and achievable objectives.

Relevant preliminary data or rationale showing feasibility.
➡️ Success predictor: A compelling scientific plan that shows the project can be completed within the budget and time.

4) Organizational Capacity

Since grants are usually awarded to organizations (not individuals), institutions must demonstrate:

Ability to execute the project and manage funds.

Administrative and ethical oversight capacity (e.g., IRBs, data management).
➡️ Success predictor: Strong institutional backing and demonstrated project management ability.

5) Patient-Centered and Health Systems Relevance

Many grants (especially in clinical and QI spaces) look for work that will:

Inform clinical practice (e.g., therapy management).

Fill gaps in diagnosis, treatment adherence, or care delivery.
➡️ Success predictor: Projects that connect evidence generation to meaningful practice change or health care improvements are more competitive.

6) Budget Justification & Responsible Use of Funds

Grant proposals must include a realistic, justified budget tied to project activities.
➡️ Success predictor: Budgets that align precisely with what is needed to answer the RFP’s questions — without excess — are favored.

🧠 Practical Tips When Preparing a Pfizer Proposal

Here’s a quick checklist for competitive Pfizer grant applications:

✔ Extract the exact research or clinical gap the RFP describes.
✔ Frame your aims to directly respond to each RFP objective.
✔ Demonstrate measurable outcomes (e.g., clinical endpoints, educational improvements).
✔ Provide solid scientific or real-world evidence rationale.
✔ Show institutional capability and compliance readiness.
✔ Justify the budget tightly against deliverables.

📌 Summary

Pfizer’s research and independent grant portfolio isn’t a general investigator funding source — it’s RFP-driven and strategic, with success heavily reliant on:

Precision fit to the published topic.

Impact on health outcomes and unmet needs.

Scientific rigor and feasibility.

Organizational strength and execution plan

Specialties

Neurosciences

Eligibility Requirements

• The following may apply: medical, dental, nursing, allied health, and/or pharmacy professional schools; healthcare institutions (both large and small); professional organizations; government agencies; and other entities with a mission related to healthcare improvement.

• Only organizations are eligible to receive grants, not individuals or medical practice groups (i.e., an independent group of physicians not affiliated with a hospital, academic institution, or professional society).

• Collaborations within institutions (e.g., between departments and/or inter-professional), as well as between different institutions / organizations / associations, are encouraged. Please note all partners must have a relevant role and the requesting organization must have a key role in the project.

• The applicant must be the Project Lead/Principal Investigator (PI) or an authorized designee of such individual (e.g., Project Lead/PI’s grant/research coordinator).

• The applicant must be a member of the American Headache Society

• The Project Lead/PI must be an employee or contractor of the requesting organization.

• Requesting organization must be legally able to receive award funding directly from Pfizer Inc. We strongly recommend that applicants confirm this with their organization or institution prior to submitting an application. Grants awarded to organizations that are subsequently found to be unable to accept funding directly from Pfizer Inc. may be subject to rescission.

Sponsor Details

Sponsor Institute/Organizations: American Headache Society

Sponsor Type: Corporate/Non-Profit

Address: 19 Mantua Rd, Mount Royal, NJ 08061

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