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Funding Opportunity




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Project Grants

Action Medical Research

Action Medical Research and Action for A-T have joined forces to provide additional funding to the Ataxia Telangiesctasia (A-T) research community. We invite applications for medical research that has the potential to benefit people with A-T.

Action Medical Research is a leading UK-wide charity dedicated to saving and changing children’s lives through medical research. Action funds a wide range of cutting-edge medical research most likely to deliver real benefit to babies, children and young people.

Action for A-T is on a mission to fund medical research to speed up the process of identifying a cure for A-T or treatments that delay or prevent the disabling effects of this devastating childhood condition.

Action Medical Research and Action for A-T invite applications for translational medical research projects that have the potential to treat or enable medical interventions for Ataxia Telangiectasia (A-T) in childhood.  Projects must be led by research-active professionals based at universities, hospitals or research institutes in any country.  The call is focused on child health, with interventions being proposed targeting babies, children and young people with A-T.

The fund aims to support high-quality projects for up to three years duration, providing a maximum of £250,000 per project.

It is anticipated that 4-5 projects will be funded through this call.

Applicants should complete an outline form, summarising their proposed research project by 28 January 2026 at 5pm. The link to the form is available here: Portal homepage - Action Medical Research. If the research proposed fits the Research Strategy of both Action Medical Research and Action for A-T, you will be invited to submit a full application.

Background

Action Medical Research is a UK-wide charity funding vital research to help babies, children and young people. For 70 years we’ve helped pioneer ways to prevent disease and develop treatments benefiting millions of people. Our research has helped to beat polio in the UK, develop ultrasound in pregnancy, fight meningitis and prevent stillbirths.  Action funds medical research in hospitals or research institutions across the UK aimed at preventing and treating disease and disability in children.

Action for A-T was established in 2012 to provide support to the wider A-T community and speed up the process of identifying a cure of treatments that delay or prevent the disabling effects of Ataxia Telangiectasia (A-T). Action for A-T’s vision is a future where the effects of A-T are minimised, and lives are transformed. They are the largest funder of A-T research in Europe, investing more the £5.7 million in 60 A-T projects around the world.

Scope

Applications are invited for translational medical research projects that have the potential to treat or enable medical interventions for Ataxia Telangiectasia (A-T) in childhood. 

Within child health, the emphasis is on clinical research or research at the interface between clinical and basic science that can be translated into clinical solutions in the short to medium term. A broad spectrum of biomedical research is suitable, with projects targeting treatments and cures, improving of diagnosis, therapies and assistive technologies being exemplars. 

Applications

Research should be both innovative and of a high standard as judged by rigorous peer review.

Applications should:

  • Address a significant, unmet need for babies or children and/or young people (CYP) with A-T.
  • Have a clearly articulated plan as to how clinical impact could be achieved within the short to medium term
  • Have a strong scientific rationale
  • Describe a discrete medical research project
  • Start from August 2026.

Smaller applications to help researchers develop original and innovative ideas are also welcome. Applications may include pilot studies that will generate data enabling larger scale applications to funding bodies or practical application.

Limitations and exclusions

We do not provide:

  • grants on social research, family relationships or socioeconomic research.
  • grants towards service provision or audit studies.
  • grants for research into complementary / alternative medicines.
  • grants purely for higher education courses.
  • grants on how best to train clinical staff.
  • grants for medical or dental electives.
  • 'top up' funding for work already supported by other funding bodies.
  • general appeals from other charities. Applications would normally come directly from research teams and projects need to be passed through our scientific peer review system.
  • applicants based in core funded units can apply but need to demonstrate added value.

We will not normally consider:

  • Projects that are similar to projects already under consideration by Action Medical Research of Action for A-T through another grant scheme.
  • Resubmissions of applications that have previously been considered by Action Medical Research or Action for A-T within one year unless a resubmission was specifically invited.
  • More than one application from the same group of researchers.

Funding and resources available

Projects may be up to 36 months in duration. 

The upper limit for funding is £250,000. It is anticipated that 4-5 projects could be funded through this call. 

Action Medical Research and Action for A-T will support the direct cost of research. Indirect or directly allocated costs such as shared equipment and resources based on estimates, administrative or other overheads (including any depreciation or maintenance costs) should not be included.

Salary costs: 

Research worker salaries can be included. 

  • Use salary scales known at the time of application and include an additional sum to cover estimates of future nationally agreed pay awards to cover cost of living increases only.  
  • Include employer’s costs, pension and national insurance and London weighting where appropriate.
  • Do not include apprenticeship levy, visa costs, costs associated with advertising and recruitment of staff or course fees for degrees.

Salary of a PI or salaries (or percentage of salaries) for those already employed in salaried long term positions should not be included. 

Consumables and Equipment: 

  • Research expenses consumables and items of dedicated equipment essential for carrying out the work can be included and must be fully justified.
  • The university or research institute should provide standard laboratory equipment and office computers.
  • VAT on consumables and equipment should not be included.

Travel, patient and public involvement and publication costs:

  • Costs of travel for researchers (excluding subsistence) may be included in an application provided they form a necessary and integral part of the research proposed
  • Do not include an allowance for attendance at meetings and conferences. (Action Medical Research grantholders may apply separately as the need arises during the grant).
  • Patient and public involvement (PPI) costs can be applied for up to a maximum of £1,000 per grant. This is in addition to any patient costs (e.g. patient recruitment costs) required to deliver the project.
  • Publication costs are limited to £3,000 per grant.

AI Based Application Success Predictor

To succeed in Action Medical Research funding competitions, applications typically demonstrate the following characteristics:

🧠 1. Clear Relevance to Child Health

Action’s mission is tightly focused on medical issues affecting babies, children and young people — successful applications must align clearly with these priorities, whether investigating disease mechanisms, clinical outcomes or technology that improves child health. Action Medical Research

Tip: Frame your research question around impact on health outcomes for the target population.

🔬 2. Innovation & Clinical or Translational Focus

Project and fellowship proposals that show novel approaches, translational potential or clear paths toward improving diagnosis, treatment, prevention or quality of life tend to rank higher with reviewers. Action Medical Research

Tip: Emphasise why the project is different from standard or incremental studies and how it bridges bench-to-bedside gaps.

📊 3. Well-Defined Objectives With Feasible Methods

Compelling proposals have specific aims, realistic timelines and a clear research design appropriate to the intended outcomes.

Components reviewed include:

Scientific rationale and background

Detailed plan and methodology

Milestones and deliverables

Suitability of host institution and team capabilities

🧑‍🎓 4. Training Component (for Fellowships)

For Research Training Fellowships, reviewers assess whether the project will substantially enhance the applicant’s skill set and equip them for future independent research. Action Medical Research

Tip: Highlight the learning outcomes, mentoring plan, and career trajectory supported by the fellowship.

🤝 5. Peer Review & Scientific Rigor

All full applications undergo external peer review. The Scientific Advisory Panel then evaluates them considering rigor, significance and potential impact. High-scoring proposals address common peer-review criteria thoroughly. Action Medical Research

💼 6. Institutional Support & Resources

Although Action does not cover indirect institutional costs, strong institutional backing (e.g., access to facilities, collaborative networks, prior successes) strengthens credibility.

🧠 Practical Application Tips

Start early: Begin preparing outline applications well before the deadline to refine aims and obtain institutional sign-off. Action Medical Research
Review past funded projects: Look at examples of previously funded research to understand scope and impact. Action Medical Research
Tailor the narrative: Make clear links between your project goals and Action’s child health priorities.
Clarify budget support: Ensure budget requests align with allowable costs (salary, consumables, dedicated equipment) and avoid indirect costs. Action Medical Research
Engage mentors: For fellowship applications, include strong supervision and training plans.

📌 Summary: Action Medical Research Success Checklist

PredictorWhy It Matters
Child health alignmentCore mission — essential eligibility and impact relevance. Action Medical Research
Innovation & translational emphasisIncreases likelihood of real-world benefit. Action Medical Research
Clear aims & methodologyReviewer confidence in feasibility. Action Medical Research
Training and career development (for fellowships)Demonstrates future impact and leadership. Action Medical Research
Scientific rigor & peer-review qualityCentral to scoring. Action Medical Research
Strong team & support environmentReinforces deliverability of outcomes.

Projects must be led by research-active professionals based at universities, hospitals or research institutes in any country.

  • Applicants, co-applicants and collaborators must be employed by hospitals, universities or research institutes.
  • The principal investigator (PI) is normally employed in a permanent position.
  • Fixed term employees on a long term contracts may be eligible to be a PI, providing the term of employment extends at least six months beyond the duration of the proposed research project and the host research institution is prepared to give all the necessary support to the individual and the project.
  • Applications from early career, independent investigators (e.g. University Lecturer within 5-years of first appointment) are encouraged.
  • Research workers who require personal support from a project grant, and who have made a substantial intellectual contribution to the grant proposal, may be named as co-applicants with an established member of staff as the PI.

Collaborations are encouraged where relevant to the project and can be at a global scale. Where appropriate, there must be plans to put in place suitable collaboration agreements. 

A research team can only apply for one grant per grant round. Applicants can be a PI on one application and co-applicant on no more than one other application.

Sponsor Institute/Organizations: Action Medical Research

Sponsor Type: Corporate/Non-Profit

Address: 5th Floor, 167-169 Great Portland Street, London, W1W 5PF

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Grant

Letter Of Intent Deadline:

Jan 28, 2026

Final Deadline:

Mar 17, 2026

Funding Amount:

$335,000

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