+ More Filters

Reset Filters

Title

Funding Organization

Funding Type

Eligible Country

Deadline

Other (Select all that apply)

Show Expired Programs

Show Verified Programs

Not Verified

CARRA-AF Flex Fund

Childhood Arthritis and Rheumatology Research Alliance (CARRA)

CARRA’s culture of collaboration focuses on facilitating, accelerating, funding, and performing research driven by academicians, clinicians, patients, and families to fulfill its mission: to conduct collaborative research to prevent, treat, and cure pediatric rheumatic diseases. CARRA’s peerreviewed grant program offers various funding opportunities to support investigators at all career levels and advance research that furthers our mission.

Program Description

In the face of federal funding cuts impacting critically needed research, CARRA has developed a rapid response supplemental grant opportunity. Offered three times a year, this funding opportunity is designed to provide timely funding support to peer-reviewed previously awarded projects that have had funding reduced or terminated within the past 12 months. Funds requested should directly support the completion of a particular aim or project element.

AI Based Application Success Predictor

Based on CARRA funding priorities and funded project patterns:

🥇 1. Strong Pediatric Rheumatology Focus (Top Predictor)

Must clearly address:
- Juvenile idiopathic arthritis (JIA)
- Pediatric lupus
- Vasculitis
- Other childhood rheumatic diseases

✔ Direct relevance to children’s outcomes is essential

🥈 2. Multicenter Collaboration (Major Advantage)

One of the strongest predictors

✔ High success:

Studies involving multiple CARRA sites

📌 Single-center studies are less competitive

🥉 3. Use of CARRA Registry/Data

Strong preference for:
- Leveraging existing registry data

✔ Predictor:

Data-driven, real-world evidence

4. Clinical / Translational Impact

Preference for:
- Patient-oriented research
- Comparative effectiveness studies

✔ Projects influencing treatment strategies score higher

5. Feasibility & Structured Study Design

Many grants are:
- Pilot or short-term

✔ Winning proposals:

Clear endpoints
Realistic timelines

6. Early Career Investigator Support

Many programs target:
- Fellows
- Junior faculty

✔ Strong mentorship is critical

7. Standardization & Protocol-Based Research

Preference for:
- Studies aligned with CARRA CTPs

8. Patient-Centered Outcomes

Strong emphasis on:
- Quality of life
- Functional outcomes

🧪 Common Funded Research Areas

Juvenile idiopathic arthritis (JIA)
Pediatric lupus
Treatment effectiveness studies
Biomarkers and disease activity
Long-term outcomes in children
Medication safety

⚠️ Common Reasons for Rejection

Weak pediatric focus
Lack of multicenter collaboration
Not leveraging CARRA resources
Poor study design
Limited clinical relevance

🧠 Bottom Line (Key Predictors Ranked)

Direct relevance to pediatric rheumatic diseases
Multicenter collaboration (very important)
Use of CARRA registry/data
Clinical/translational impact
Feasible, well-designed study
Strong mentorship (early-career grants)

Specialties

Rheumatology

Eligibility Requirements

• The project principal investigator (PI) must be a CARRA member in good standing (up to date on membership dues and member profile is current and accurate).

• The following current CARRA members are eligible to serve as PIs on Flex Fund Awards:

o Pediatric rheumatologists

o Fellows

• Applicants must hold an advanced degree (MD or equivalent, PhD, or MD/PhD) While not eligible to serve as PIs, the following may serve as team members: medical and graduate students, research professional members who are regulatory or data coordinators, business and industry associate members, and nonprofit/government associate members.

• CARRA board members or those in executive leadership positions may not serve as study leadership.

• Previous and current CARRA awardees who wish to submit new grant applications must be up to date on all award deliverables.

Sponsor Details

Sponsor Institute/Organizations: Childhood Arthritis and Rheumatology Research Alliance (CARRA)

Sponsor Type: Corporate/Non-Profit

Address: 1050 Connecticut Avenue, NW, Suite 500 Washington, DC 20036

Legal & Affiliation Disclaimer

Affiliation Disclaimer: Trialect operates independently and is not affiliated with, endorsed by, or supported by any sponsors or organizations posting on the GrantsBoard platform. As an independent aggregator of publicly available funding opportunities, Trialect provides equal access to information for all users without endorsing any specific funding source, content, organization, or sponsor. Trialect assumes no responsibility for the content posted by sponsors or third parties.

Subscription Disclaimer: Upon logging into Trialect, you may choose to SUBSCRIBE to GrantsBoard for timely notifications of funding opportunities and to access exclusive benefits, such as priority alerts, reminders, personalized recommendations, and additional application support. However, users are advised to contact sponsors directly for any questions and are not required to subscribe to engage with funding opportunities.

Content Ownership and Copyright Disclaimer: Trialect respects the intellectual property rights of all organizations and individuals. All content posted on GrantsBoard is provided solely for informational purposes and remains the property of the original owners. Trialect does not claim ownership of, nor does it have any proprietary interest in, content provided by third-party sponsors. Users are encouraged to verify content and ownership directly with the posting sponsor.

Fair Use Disclaimer: The information and content available on GrantsBoard are compiled from publicly accessible sources in alignment with fair use principles under U.S. copyright law. Trialect serves as an aggregator of this content, offering it to users in good faith and with the understanding that it is available for public dissemination. Any organization or individual who believes their intellectual property rights have been violated is encouraged to contact us for prompt resolution.

Third-Party Posting Responsibility Disclaimer: Trialect is a neutral platform that allows third-party sponsors to post funding opportunities for informational purposes only. Sponsors are solely responsible for ensuring that their postings comply with copyright, trademark, and other intellectual property laws. Trialect assumes no liability for any copyright or intellectual property infringements in third-party content and will take appropriate action to address any substantiated claims.

Accuracy and Verification Disclaimer: Trialect makes no warranties regarding the accuracy, completeness, or reliability of the information provided by sponsors. Users are advised to verify the details of any funding opportunity directly with the sponsor before taking action. Trialect cannot be held liable for any discrepancies, omissions, or inaccuracies in third-party postings.

Notice and Takedown Policy: Trialect is committed to upholding copyright law and protecting the rights of intellectual property owners. If you believe that content on GrantsBoard infringes your copyright or intellectual property rights, please contact us with detailed information about the claim. Upon receipt of a valid notice, Trialect will promptly investigate and, where appropriate, remove or disable access to the infringing content.

View Funding Opportunity