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Cardiac Sarcoidosis Grant

Foundation for Sarcoidosis Research

The FSR Cardiac Grant for sarcoidosis research is now accepting Letters of Intent (LOIs) for the 2026 cycle! Submit by 11:59pm EST on June  4, 2026!

The FSR Cardiac Grant began in 2022. This opportunity allows for researchers to apply with an existing or new project and aims to support smaller scale or pilot research projects dedicated to cardiac sarcoidosis, which can be funded either singularly by FSR or through a partnership with additional funders. Each proposal should feature a $100,000 project over a two-year period.

Applicants must submit a Letter of Intent (LOI) to be considered for funding. You will be notified by late July if you are invited to submit a full grant proposal. Full applications will not be accepted unless notification of invitation has been received from FSR.

Restrictions

The budget for the FSR Pilot Grant is limited to $100,000 and may include up to 10% indirect costs.
Compensation for personnel—including principal investigators, co-investigators, and key study staff—may not exceed the NIH salary limitation in effect at the time of award.
Budgets that include research lab equipment that utilizes over 50% of the proposed budget must include justification and a description of how that equipment will be used in the post-grant period.
All awardees must submit bi-annual progress and financial reports to FSR. Bi-annual reports are due at the end of each 6-month period while the grant period is active.
Projects proposed may not be longer than two years in duration.
Successful applicants may not hold any other research funding from FSR at the time funding of this grant begins. This includes funding from the FSR Established Investigator, Early Career Fellowship Grant, Pilot Grant, and Cardiac Grant. However, FSR Clinical Data Registry investigators may apply.
PIs and Co-PIs may not submit more than one application for this program in a given cycle.

AI Based Application Success Predictor

🫁 1. Strong Focus on Sarcoidosis (Non-Negotiable)

Projects must directly address:
- Sarcoidosis
Includes:
- Pulmonary sarcoidosis
- Cardiac sarcoidosis
- Neurosarcoidosis
- Multisystem inflammatory disease

👉 General pulmonary or autoimmune research without sarcoidosis relevance → low success probability

🎯 2. Clear Translational & Patient Impact (Top Predictor)

Foundation for Sarcoidosis Research strongly prioritizes:
- Research that can:
  - Improve diagnosis
  - Advance treatment
  - Improve quality of life
  - Accelerate clinical care

👉 Key question:
“Will this improve outcomes for patients living with sarcoidosis?”

🔄 3. Therapeutic Development & Clinical Translation (Critical)

One of the strongest strategic priorities:

New treatment strategies
Clinical trial readiness
Precision medicine approaches
Drug repurposing

👉 Pure descriptive/basic inflammatory biology without translational direction is less competitive.

🧬 4. Biomarkers & Diagnostic Innovation (Major Differentiator)

High-success areas include:

Biomarker discovery
Imaging advancements
Disease activity monitoring
Predictive diagnostics
Multi-organ disease assessment

👉 Clinical endpoint and biomarker work is highly valued.

🌍 5. Patient-Centered Outcomes & Quality of Life

Strong emphasis on:
- Fatigue
- Functional impairment
- Symptom burden
- Mental health and daily living

👉 Patient-centered sarcoidosis outcomes research performs very well.

👩‍🔬 6. Rare Disease & Multidisciplinary Expertise

Competitive investigators often have:

Expertise in:
- Pulmonology
- Immunology
- Rheumatology
- Cardiology
- Neurology

👉 Multisystem sarcoidosis expertise strengthens applications.

🤝 7. Collaboration with Sarcoidosis Clinics & Patient Networks

Strong projects often involve:

Sarcoidosis centers
Rare disease consortia
Patient registries
Multicenter collaboration

👉 Access to sarcoidosis patient populations significantly improves feasibility.

🚀 8. Innovation in Immunology & Precision Medicine

Growing priority areas include:

Immune profiling
Molecular phenotyping
AI/data-driven sarcoidosis classification
Personalized treatment approaches

👉 Precision inflammatory medicine approaches are increasingly competitive.

📊 9. Feasible, Pilot-Scale Rare Disease Research

FSR commonly funds:
- Pilot studies
- Early translational projects
- Seed funding initiatives

👉 Realistic recruitment, timelines, and milestones are essential.

👩‍⚕️ 10. Healthcare Access & Equity in Rare Disease Care

Increasing emphasis on:

Diagnostic delays
Access disparities
Minority patient burden
Rural/underserved populations

👉 Health equity framing strengthens competitiveness.

📈 11. Potential for NIH/Industry Follow-On Funding

FSR funding frequently serves as:
- Preliminary support for:
  - NIH grants
  - industry-sponsored trials
  - multicenter therapeutic studies

👉 Scalability and future translational potential matter greatly.

🌐 12. Dissemination & Community Engagement

Competitive proposals often include:

Patient education
Data sharing
Advocacy integration
Publication and conference plans

👉 Rare disease community connection is highly valued.

📊 Summary: Key Predictors (Ranked)

🔥 Highest impact factors:

Sarcoidosis-specific focus
Translational/patient impact relevance
Therapeutic or diagnostic advancement potential

⚖️ Major differentiators:

Biomarker and precision medicine integration
Patient-centered outcomes
Multidisciplinary rare disease expertise

📌 Supporting factors:

Collaboration with sarcoidosis networks
Feasibility in rare disease context
Health equity relevance
Future NIH/industry scalability

💡 Insider Insight

Compared to NIH pulmonary/immunology funders:

Foundation for Sarcoidosis Research is:
👉 highly focused on:
- practical sarcoidosis impact
- translational therapeutics
- rare disease collaboration
- patient-centered care improvement

👉 Winning formula:
Sarcoidosis-focused translational project + diagnostic/therapeutic relevance + patient-centered outcomes + strong rare disease feasibility

Specialties

Others

Pulmonology

Eligibility Requirements

Proposals for the FSR Cardiac Grant must be for research that focuses on cardiac sarcoidosis. We invite clinician scientists from any related disciplines to apply (e.g., radiology, electrophysiology).
Proposals for research studies focused on areas other than cardiac sarcoidosis are not eligible.
Principal Investigators (PIs), Co-PIs, and Sub-Is, must submit bio-sketches in the NIH format (or equivalent international formats) as well as any letters of support from anyone collaborating on the proposal.
The PI must be affiliated with a college, university, or a non-profit research facility that is willing to serve as the administering organization if the grant is awarded.
Proposals are accepted from the U.S. and internationally, however all proposals must be submitted in English and budgets must be proposed in U.S. Dollars.

Sponsor Details

Sponsor Institute/Organizations: Foundation for Sarcoidosis Research

Sponsor Type: Corporate/Non-Profit

Address: 320 W Ohio St., Suite 300 Chicago, IL 60654

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