Trialect

Active

Metabolomics

Alabama State University (ASU)

Dr. Daniel A. Abugri is an Assistant Professor of Microbiology at Alabama State University (ASU) and the Principal Investigator of the Laboratory of Ethnomedicine, Parasitology, and Drug Discovery. His specialized research program explores the intersection of functional lipidomics, cellular membrane dynamics, and natural product drug discovery.

Main Areas of Interest

Polar Metabolic Networks: Mapping primary and secondary metabolites across kingdoms.
Mechanism of Action Studies: Tracking how pathogens respond metabolically to novel antimicrobial drugs.
Natural Product Translation: Characterizing bioactive plant and fungal extracts for clinical applications.
Host-Pathogen Interactions: Analyzing chemical signaling and nutrient competition between hosts and parasites.

Specialties

Biochemistry

Biomedical Engineering

Cell Biology

Microbiology

Molecular Biology

Techniques You Will Learn

Quenching & Extraction: Extracting polar and semi-polar metabolites while preserving volatile compounds.
Bioactive Compound Profiling: Quantifying specific chemical families like phenolics, flavonoids, and alkaloids.
Antimicrobial Functional Assays: Conducting in vitro screens to link specific metabolites to pathogen inhibition.
Chemometrics & Statistics: Applying multivariate statistics like PCA and PLS-DA to complex metabolic profiles.
Metabolite Annotation: Querying mass spectrometry fragments against databases like HMDB, MoNA, and GNPS.

Modules

Module 1: Sample Preparation & Extraction Dynamics

Core Focus: Quenching metabolic activity and preserving chemical integrity.
Key Concept: Optimizing extraction protocols for polar and semi-polar metabolites.
Practical Skill: Isolating volatile compounds without thermal degradation or sample loss.

Module 2: Profiling Bioactive Natural Products

Core Focus: Characterizing complex plant and fungal extracts for clinical translation.
Key Concept: Biosynthesis and function of secondary metabolites across diverse kingdoms.
Practical Skill: Quantifying targeted chemical families including phenolics, flavonoids, and alkaloids.

Module 3: Advanced Mass Spectrometry & Metabolite Annotation

Core Focus: Data acquisition and structural identification of unknown compounds.
Key Concept: Tandem mass spectrometry fragmentation patterns and chemical spectral libraries.
Practical Skill: Querying raw MS fragments against public databases like HMDB, MoNA, and GNPS.

Module 4: Chemometrics & Multivariate Data Analysis

Core Focus: Transforming complex mass spectrometry datasets into biological insights.
Key Concept: Variance, dimensionality reduction, and pattern recognition in chemical profiles.
Practical Skill: Building and validating statistical models using PCA and PLS-DA software.

Module 5: Pathogen Influx, Drug Mechanisms, & Host Interactions

Core Focus: Functional assays to map nutrient competition and antimicrobial action.
Key Concept: Tracking chemical signaling and host-parasite metabolic networks under drug stress.
Practical Skill: Designing in vitro screening assays to link specific metabolites to pathogen inhibition.

Program Fee


Total Number of Modules	5
Total Program Cost	$650.00

Who Can Apply

Academic Level: Postdoctoral researchers, PhD/Master's candidates, or advanced chemistry/biology undergraduate seniors.
Field of Study: Biochemistry, analytical chemistry, microbiology, parasitology, or bioinformatics.
Technical Prerequisites: Prior laboratory experience with chemical extractions, sterile cell-culturing, or data analysis software.

Host Details

Host Name: Abugri Daniel

Affiliation: Alabama State University (ASU)

Address: Alabama State University915 S. Jackson StreetMontgomery, AL 36104

Website URL:

Disclaimer:It is mandatory that all applicants carry workplace liability insurance, e.g., https://www.protrip-world-liability.com (Erasmus students use this package and typically costs around 5 € per month - please check) in addition to health insurance when you join any of the onsite Trialect partnered fellowships.

Legal & Affiliation Disclaimer

Affiliation Disclaimer: Trialect operates independently and is not affiliated with, endorsed by, or supported by any sponsors or organizations posting on the GrantsBoard platform. As an independent aggregator of publicly available funding opportunities, Trialect provides equal access to information for all users without endorsing any specific funding source, content, organization, or sponsor. Trialect assumes no responsibility for the content posted by sponsors or third parties.

Subscription Disclaimer: Upon logging into Trialect, you may choose to SUBSCRIBE to GrantsBoard for timely notifications of funding opportunities and to access exclusive benefits, such as priority alerts, reminders, personalized recommendations, and additional application support. However, users are advised to contact sponsors directly for any questions and are not required to subscribe to engage with funding opportunities.

Content Ownership and Copyright Disclaimer: Trialect respects the intellectual property rights of all organizations and individuals. All content posted on GrantsBoard is provided solely for informational purposes and remains the property of the original owners. Trialect does not claim ownership of, nor does it have any proprietary interest in, content provided by third-party sponsors. Users are encouraged to verify content and ownership directly with the posting sponsor.

Fair Use Disclaimer: The information and content available on GrantsBoard are compiled from publicly accessible sources in alignment with fair use principles under U.S. copyright law. Trialect serves as an aggregator of this content, offering it to users in good faith and with the understanding that it is available for public dissemination. Any organization or individual who believes their intellectual property rights have been violated is encouraged to contact us for prompt resolution.

Third-Party Posting Responsibility Disclaimer: Trialect is a neutral platform that allows third-party sponsors to post funding opportunities for informational purposes only. Sponsors are solely responsible for ensuring that their postings comply with copyright, trademark, and other intellectual property laws. Trialect assumes no liability for any copyright or intellectual property infringements in third-party content and will take appropriate action to address any substantiated claims.

Accuracy and Verification Disclaimer: Trialect makes no warranties regarding the accuracy, completeness, or reliability of the information provided by sponsors. Users are advised to verify the details of any funding opportunity directly with the sponsor before taking action. Trialect cannot be held liable for any discrepancies, omissions, or inaccuracies in third-party postings.

Notice and Takedown Policy: Trialect is committed to upholding copyright law and protecting the rights of intellectual property owners. If you believe that content on GrantsBoard infringes your copyright or intellectual property rights, please contact us with detailed information about the claim. Upon receipt of a valid notice, Trialect will promptly investigate and, where appropriate, remove or disable access to the infringing content.