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Funding Opportunity




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UKRI Translation: MRC Impact Acceleration Awards

UK Research and Innovation

Opportunity status:

Open

Funders:

Medical Research Council (MRC)

Funding type:

Grant

Award range:

£50,000 - £300,000

Publication date:

16 July 2026

Opening date:

16 July 2026 9:00am UK time

Closing date:

11 November 2026 4:00pm UK time

Apply to the MRC Impact Acceleration Award for single-step support in developing a new or repurposed medicine, medical device, diagnostic, or other medical product.

Projects must target a high-risk development step backed by prior funding, generating critical data to de-risk onward progression or determine failure.

The Impact Acceleration Award strategically bridges the smaller Impact Acceleration Account (IAA) and the larger Proof of Concept funding opportunity.

You must be based at a Medical Research Council (MRC) eligible research organisation.

This funding opportunity was formerly known as ‘Gap Fund: single-step support for medical product development’.

AI Based Application Success Predictor

1. Alignment with the specific funding opportunity (Highest Predictor ⭐⭐⭐⭐⭐)

This is the most important predictor.

Competitive proposals closely match:

  • The objectives of the funding opportunity
  • Council-specific priorities (e.g., MRC, EPSRC, ESRC)
  • Eligibility requirements
  • Scope and remit
  • Assessment criteria

A scientifically excellent proposal that does not fit the published scope is unlikely to be funded.

2. Research excellence and importance (Highest Predictor ⭐⭐⭐⭐⭐)

UKRI evaluates whether the research:

  • Addresses an important problem
  • Advances knowledge significantly
  • Is intellectually ambitious
  • Has the potential to influence the field

Reviewers assess the originality, significance, and quality of the proposed research.

3. Innovation and originality (Highest Predictor ⭐⭐⭐⭐⭐)

Competitive proposals typically demonstrate:

  • Novel concepts
  • Innovative methodologies
  • Creative approaches
  • Transformative ideas
  • High scientific ambition

UKRI supports both curiosity-driven discovery research and innovative applied research, depending on the funding opportunity.

4. Strong methodology and feasibility (Very High Predictor ⭐⭐⭐⭐⭐)

Applications should provide:

  • Well-defined objectives
  • Robust study design
  • Appropriate analytical methods
  • Risk management strategies
  • Realistic timelines
  • Clearly justified resources

Reviewers expect a convincing plan for delivering the proposed work.

5. Applicant and team capability (Very High Predictor ⭐⭐⭐⭐⭐)

UKRI's assessment framework places strong emphasis on the ability of the applicant and team to deliver the project.

Competitive teams demonstrate:

  • Relevant expertise
  • Strong publication record
  • Leadership experience
  • Complementary skills
  • Appropriate collaborations

For early-career schemes, reviewers evaluate potential rather than only past achievements.

6. Positive research environment and institutional support (Very High Predictor ⭐⭐⭐⭐⭐)

Reviewers consider whether the research environment provides:

  • Appropriate infrastructure
  • Institutional commitment
  • Access to facilities
  • Mentoring (where applicable)
  • Technical support
  • Collaborative opportunities

The host organization should clearly demonstrate its ability to support successful project delivery.

7. Potential impact and pathways to impact (Very High Predictor ⭐⭐⭐⭐⭐)

Although UKRI has moved away from the separate "Pathways to Impact" document, proposals are still expected to explain how the research could generate benefits.

Competitive applications describe potential impacts such as:

  • Improvements to health
  • Economic growth
  • Environmental sustainability
  • Public policy
  • Industry innovation
  • Societal benefit
  • Cultural impact

The expected impact should be appropriate to the research stage and funding opportunity.

8. Interdisciplinary collaboration and partnerships (High Predictor ⭐⭐⭐⭐☆)

UKRI increasingly encourages interdisciplinary research.

Competitive projects often involve:

  • Multiple research disciplines
  • Industry partners
  • NHS organizations
  • Government agencies
  • International collaborators
  • Public and third-sector organizations

Cross-sector collaboration is especially important for large strategic and challenge-led programs.

9. Responsible research and innovation (RRI), equality, diversity, and inclusion (EDI), and open research (High Predictor ⭐⭐⭐⭐☆)

UKRI expects applicants to consider:

  • Responsible research and innovation
  • Equality, diversity, and inclusion
  • Ethical issues
  • Environmental sustainability
  • Open research practices
  • Data sharing and management

These considerations strengthen the overall quality and credibility of the proposal.

10. Realistic resources and value for money (High Predictor ⭐⭐⭐⭐☆)

Reviewers assess whether:

  • The requested budget is appropriate
  • Resources are well justified
  • Staffing is realistic
  • Equipment requests are necessary
  • The project offers good value for public funding

Strong justification of resources is an important component of UKRI review.

This opportunity is open to organisations with standard eligibility. Check if your organisation is eligible.

Who is eligible to apply

To be eligible to apply for this funding opportunity you must:

  • show that you will direct the project and be actively engaged in the work
  • be looking to generate critical preliminary data to build confidence in the development strategy for a new medicine, repurposed medicine, medical device, diagnostic test, or other medical intervention development

For applicants who do not have a contract of employment for the duration of the proposed project, by submitting an application the research organisation is confirming, if it is successful:

  • contracts will be extended beyond the end date of the project
  • all necessary support for the project and the applicants will be provided, including mentorship and career development for early career researchers

Demand management

You can only submit one application as project lead to this funding opportunity.

Resubmissions

We will not accept uninvited resubmission of applications that were submitted after 1 April 2026 to MRC, the rest of UK Research and Innovation (UKRI) or any other funder. An uninvited resubmission is an application that was previously unsuccessful and has been submitted again without being invited by MRC. This includes applications that are unchanged, minimally revised, or substantially the same as the original submission. Uninvited resubmissions will be rejected.

You should contact us if you are unsure whether your application is a resubmission. Find contacts in the ‘contact details’ section

Who is not eligible to apply

You are not eligible to apply for this funding opportunity as a project lead if you are based at an international research organisation. This does not include the MRC Unit The Gambia at the London School of Hygiene and Tropical Medicine (LSHTM) or MRC/UVRI (Uganda Virus Research Institute) and LSHTM Uganda Research Unit.

If you are employed by these organisations you cannot apply as project lead or project co-lead, but can participate as project partners on an application led by an eligible UK organisation:

  • businesses
  • charity and third sector organisations

However, charities and third sector organisations that are approved UKRI Independent Research Organisations are eligible to apply as project lead or project co-lead.

International researchers

As MRC is a lead funder for this funding opportunity, international researchers can apply as ‘project co-lead (international)’. You should include all other international collaborators (or UK partners not based at approved organisations) as project partners.

Project co-leads (international) make a major intellectual contribution to the design or conduct of the project. Their contribution and added value to the research collaboration should be clearly explained and justified in the application, see ‘Applicant and team capability to deliver’.

Read the UKRI project co-lead (international) eligibility for more details. Please contact us if you are uncertain about eligibility.

Equality, diversity and inclusion

We are committed to achieving equality of opportunity for all funding applicants. We encourage applications from a diverse range of researchers.

We support people to work in a way that suits their personal circumstances. This includes:

  • career breaks
  • support for people with caring responsibilities
  • flexible working
  • alternative working patterns

UKRI can offer disability and accessibility support for UKRI applicants and grant holders during the application and assessment process.

Eligible Countries:

Sponsor Institute/Organizations: UK Research and Innovation

Sponsor Type: Corporate/Non-Profit

Address: Polaris House, North Star Avenue, Swindon SN2 1FL

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Grant

Letter Of Intent Deadline:

Nov 11, 2026

Final Deadline:

Nov 11, 2026

Funding Amount:

$403,399

up to £300,000

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