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Travel Grants

Alpha-1 Foundation

The Alpha-1 Foundation is the world’s #1 funder of Alpha-1 research, including Alpha-1 related lung and liver disease.

Grants from the Alpha-1 Foundation support rigorous scientific research to advance Alpha-1 treatment and care and draw us closer to a cure. The Alpha-1 Foundation also funds research into ethical, legal, and social issues impacting people with genetic conditions.

2025 – 2026 In-Cycle Grants Award Program

The Alpha-1 Foundation Grants Award Program funds a wide range of meritorious research efforts designed to improve the health of individuals with AAT Deficiency with the ultimate goal of finding a cure.

The Foundation accepts and reviews Letter of Intent (LOI) submissions during the beginning of our annual grant cycle and selected LOIs are invited to submit a full proposal.

Travel Grants:

Up to $1,000
1. Objective: Support travel to attend national and international scientific conferences or meetings to present AAT-related abstracts or
2. Objective: Support cross-training at an established Alpha-1 laboratory by an established Alpha-1 investigator

AI Based Application Success Predictor

1. 🎯 Direct Relevance to Alpha-1 Antitrypsin Deficiency

Successful projects focus on:

Molecular and genetic mechanisms of AATD

Novel therapeutics, gene therapy, or augmentation approaches

Disease modifiers for COPD, liver disease, or other AATD complications

Development of diagnostic tools and biomarkers

✅ Predictor: Research is explicitly tied to Alpha-1 pathophysiology, detection, or treatment.

2. 🧪 Strong Preliminary Data and Feasibility

Competitive applicants provide proof-of-concept studies or pilot data

Feasible aims within a 1–2 year grant period

Use of patient samples, animal models, or robust in vitro studies

✅ Predictor: Proposal demonstrates scientific rigor and clear deliverables.

3. 👩‍🔬 Focus on Early-Career Investigators

The Alpha-1 Foundation strongly supports:

Postdoctoral fellows and junior faculty

Early-stage researchers seeking pilot funding to generate data for NIH or other large grants

✅ Predictor: You’re an emerging scientist with strong mentorship support.

4. 🤝 Collaboration with Alpha-1 Networks

Use of Alpha-1 Foundation Research Registry, Clinical Resource Centers, or patient samples

Partnerships with clinicians, geneticists, and translational researchers

✅ Predictor: The proposal integrates with Alpha-1 Foundation infrastructure or collaborators.

5. 📢 Potential for Translational Impact

Preference for projects that bridge basic research to therapy or diagnostics

Focus on real-world applicability for patients

✅ Predictor: You clearly outline how results could improve care or lead to new treatments.

🧾 Alpha-1 Foundation Grant Programs

Program	Amount	Audience	Purpose
Pilot and Feasibility Grants	$40,000–$75,000	Early-career investigators	Generate preliminary data
Postdoctoral Fellowship	$40,000–$50,000	Postdocs	1–2 years of training
Research Grants	~$100,000/year	Faculty	Mechanistic or translational studies
Bridge Grants	~$50,000	Investigators with near-miss NIH applications	Keep research funded temporarily

🧬 Commonly Funded Topics

Gene therapy and gene editing for AATD

Augmentation therapy optimization

Understanding liver and lung disease progression

Newborn screening or early diagnostic tools

Alpha-1 biomarkers for clinical trials

📌 Tips for Strong Applications

✅ Emphasize how your work aligns with Alpha-1 priorities
✅ Include mentorship letters for early-career grants
✅ Plan for leveraging pilot data for NIH or industry funding
✅ Engage Alpha-1 patient registries or clinical networks

Specialties

Others

Pulmonology

Eligibility Requirements

Alpha-1 Foundation provides grants to support travel to attend national and international scientific conferences or meetings to present AAT-related abstracts and to support cross-training at an established Alpha-1 laboratory by an established Alpha-1 investigator.

Sponsor Details

Sponsor Institute/Organizations: Alpha-1 Foundation

Sponsor Type: Corporate/Non-Profit

Address: 3300 Ponce de Leon Blvd. Coral Gables, Florida 33134

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