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The SWOG/Hope Foundation Impact Award

Hope Foundation for Cancer Research

SWOG Cancer Research Network’s mission is to improve the practice of cancer medicine in preventing, detecting, and treating cancer, and to enhance the quality of life for cancer survivors, primarily through design and conduct of clinical trials. SWOG is a National Cancer Institute-supported network of cancer researchers at more than 1,300 sites in the U.S., Canada, and beyond. Additional educational and cancer research support is provided by SWOG’s non-profit philanthropic partner, The Hope Foundation for Cancer Research.

The SWOG/Hope Foundation Impact Award is a funding program from The Hope Foundation that encourages novel and innovative SWOG research by supporting early and conceptual stages of these projects. The work proposed should use resources from completed SWOG trials or be directly translatable to clinical trials in SWOG and the NCTN in the foreseeable future.

Awards are issued through a competitive peer-review process that includes SWOG and Hope Foundation leaders as well as externally nominated reviewers, as necessary.

Individual projects are funded for up to $250,000 (total cost) and may be spent over a 2-year award period. Funding for smaller feasibility projects that are critical to the conduct of future SWOG trials are also encouraged. Indirect costs are included in the total award and limited to a rate of 25%. The number of awards and duration of program is contingent upon available funding at SWOG and The Hope Foundation.

KEY DATES LOI Deadline: January 15 at 5pm ET Full Application Deadline: Determined upon invitation Award Period: June 1-May 31

AI Based Application Success Predictor

Core mission: Increase participation of underrepresented groups in STEM graduate education.

Top success predictors

Clear STEM degree trajectory (MS/PhD) with strong academic preparation

Compelling personal statement linking background, barriers, and STEM goals

Demonstrated commitment to diversity, equity, and inclusion (mentoring, outreach, service)

Well-defined career plan showing long-term impact in STEM

Strong letters of recommendation emphasizing resilience, leadership, and research potential

Common pitfalls

Generic DEI statements without concrete examples

Weak alignment between proposed field and long-term goals

❤️ Heart Research UK

Core mission: Support innovative research to prevent, treat, and manage heart disease (UK-focused).

Top success predictors

Clear translational relevance to cardiovascular disease outcomes

Innovative but feasible pilot-scale studies

Strong methodology and statistics, appropriate to limited budgets

Early-career investigator leadership with senior mentorship

Clear plan for next-step funding (NIHR/MRC/BHF)

Common pitfalls

Overambitious scope for grant size

Weak clinical relevance or unclear patient benefit

🩸 Hemostasis & Thrombosis Research Society (HTRS)

Core mission: Advance research and training in bleeding and clotting disorders.

Top success predictors

Direct relevance to hemostasis/thrombosis or rare bleeding disorders

Clear clinical or translational focus (bench-to-bedside favored)

Early-career investigator development (career development grants are key)

Strong mentorship and access to patient populations or registries

Practical, well-powered study design

Common pitfalls

Projects drifting into general hematology without a hemostasis focus

Insufficient mentorship structure

🧠 Hillblom (Larry L.) Foundation

Core mission: Accelerate research on neurodegenerative diseases (Alzheimer’s, Parkinson’s, ALS, FTLD).

Top success predictors

High-risk / high-reward scientific ideas

Clear disease relevance with mechanistic insight

Strong PI creativity and independence (often early- to mid-career)

Concise, elegant experimental plans

Potential to generate transformative insights, not incremental work

Common pitfalls

Incremental extensions of existing projects

Weak justification of novelty or disease relevance

🎗️ Hope Foundation for Cancer Research

Core mission: Support early-career investigators and innovative cancer research.

Top success predictors

Early-career PI with strong upward trajectory

Innovative hypothesis with clear translational relevance

Focused aims achievable within short funding period

Strong mentorship and institutional support

Clear path to NIH or major foundation follow-on funding

Common pitfalls

Overly descriptive or exploratory proposals

Lack of long-term vision beyond the pilot project

🔑 Cross-cutting patterns across all these funders

Across these programs, funded applications consistently show:

Clear mission alignment (this matters more than prestige)

Feasible scope matched to modest grant sizes

Strong narrative linking people → problem → impact

Evidence the funding will be career- or field-changing, not just supportive

Specialties

Clinical Trials

Pulmonology

Eligibility Requirements

Any SWOG member investigator eligible for NIH funding is encouraged to submit to this program. Awardees will be expected to present their work at one or more semiannual SWOG group meetings and to adhere to Group policies and procedures as applicable to the project.

Sponsor Details

Sponsor Institute/Organizations: Hope Foundation for Cancer Research

Sponsor Type: Corporate/Non-Profit

Address: 24 Frank Lloyd Wright Drive P.O. Box 483 (Suite 4300K) Ann Arbor, Michigan 48105

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