The St. Baldrick's Foundation is a volunteer and donor powered charity committed to supporting the most promising research to find cures for childhood cancers and give survivors long and healthy lives. It started with a friendly dare: would you shave your head to raise money for kids’ cancer research? What happened next would change the world. This bold act of baldness has gained major momentum, since its start in 2000. Today, we have more than 1,000 head-shaving events taking place around the world – virtually and at pubs, restaurants, schools, churches, parks, firehouses, military bases – you name it. It is our constituents’ way of changing the world, in a meaningful way. Volunteers also raise funds through athletic challenges, livestream fundraisers and many other activities. Since the Foundation's first grants as an independent charity in 2005, St. Baldrick's has invested more than $368 million in childhood cancer research grants worldwide. It’s about collaboration. It’s about powerful ideas, big and small. It’s about never giving up until we have cures for all kids with cancers.
FUNDING HIGHLIGHTS
The St. Baldrick’s Foundation works hard to be sure that every dollar makes the biggest impact possible in childhood cancer research. The Foundation is proud to have received the National Cancer Institute Peer Review Funder designation for selection of grants. The Foundation has held several Research Priorities Summits with many of the country’s leading pediatric oncology researchers participating to advise the staff and board of directors on funding priorities.
The St. Baldrick’s team and scientific advisors meet regularly to be sure St. Baldrick’s funds make the greatest impact on pediatric cancer research.
Current funding priorities are divided into four categories:
• New discovery research
• Translational research and early phase clinical trials
• Phase III clinical trials & infrastructure support of participating institutions (primarily the fall grant cycle)
• Education of new pediatric oncology researchers
In addition to research to understand the biology of childhood cancers and discover leads to more effective treatments, topics of interest include, but are not limited to:
• Adolescents & young adults
• Survivorship, outcomes, and quality of life
• Supportive care
• Epidemiology and pediatric cancer predispositions
• Precision medicine
• Alternative & complementary therapies
The top predictor is that the project specifically benefits pediatric/AYA cancer patients, including:
Leukemias (ALL, AML)
Brain & CNS tumors (medulloblastoma, glioma, DIPG/DMG)
Neuroblastoma
Sarcomas (osteosarcoma, Ewing, RMS)
Lymphoma
Rare pediatric malignancies (histiocytic disorders, germ cell tumors)
High-priority themes:
Relapsed/refractory disease
Drug resistance mechanisms
Targeted and immunotherapies
Minimal residual disease detection
Novel biomarkers
Treatment toxicity reduction & survivorship
Neurocognitive, endocrine, psychosocial outcomes
❗ Adult oncology projects with children as a subpopulation do not score well.
Perfect match matters:
| Mechanism | Best For | Critical Criteria |
|---|---|---|
| St. Baldrick’s Fellows | Pediatric oncology trainees | Mentorship + training environment |
| Early Career / Scholar Awards | Junior faculty | Trajectory → independent funding |
| Translational/Consortium | Established investigators & multi-site teams | Patient access + clinical impact |
| Supportive Care Grants | Clinicians & outcomes researchers | QoL, toxicity mitigation, disparities |
Predictor: Fit PI career stage, project maturity, and patient access to the exact call.
Even pilot grants show:
Feasibility proven in models or early trials
Early biomarker signals
Evidence that required assays, recruitment, and collaborations are established
Target expression or mechanistic rationale validated in pediatric tumors
Predictor: Feasibility and strong rationale → major scoring factor.
Winning proposals leverage:
Patient-derived xenografts (PDX) from children
Pediatric tumor cell lines or organoids
Multi-omics data from pediatric tumors
Access to biobanks, Children’s Oncology Group (COG), pediatric trial groups
Defined cohort recruitment strategy for clinical studies
Predictor: Authentic pediatric relevance is essential.
St. Baldrick’s wants to change outcomes, not only understand disease.
Funded proposals show:
Clear route to trials within 3–5 years
IND-enabling milestones if drug-focused
Biomarker validation toward clinical utility
Defined endpoints to prove patient benefit
Predictor: Promising pathway to clinical impact increases enthusiasm.
Reviewers reward:
Publications in pediatric oncology
Prior success in grant delivery
Unique expertise aligned to the project
Clear development into a leader in childhood cancer research
Predictor: PI quality is heavily weighted, especially for Scholar/Faculty awards.
Critical criteria:
Well-funded primary mentor with pediatric oncology leadership
Protected time for research
Robust institutional infrastructure (cores, patients, imaging, GMP if needed)
Co-mentors for complementary skillsets
Predictor: Mentor strength influences reviewer confidence.
Best proposals include:
2–3 hypothesis-driven aims
Rapid, measurable milestones
Clear go/no-go decisions
Realistic for 1–3 year timelines
Plan for future funding (NIH/DOD/COG)
Predictor: Feasibility & clarity are top scoring criteria.
St. Baldrick’s seeks transformative solutions:
First-in-field mechanistic insights
Novel cell/gene therapies
Combination regimens addressing resistance
Real-world solutions to survivorship harms
Cross-disciplinary technologies
Predictor: Innovation + urgent clinical need = reviewer enthusiasm.
Winning proposals are:
Logically structured
Supported by visual preliminary data
Strong in rigor & methodology
Accessible to both clinicians and laboratory reviewers
Compliant with guidelines & page limits
Predictor: Clean writing often separates top-tier applications.
| Predictor | Why It Matters |
|---|---|
| Pediatric cancer focus | Core mission |
| Mechanism alignment | Correct evaluation |
| Preliminary data | Feasibility validation |
| Pediatric models | Clinical relevance |
| Translational path | Near-term patient benefit |
| PI trajectory | Investment return |
| Mentorship & environment | Execution & independence |
| Feasible aims | Deliverable results |
| Innovation | Big impact potential |
| Strong writing | Higher reviewer scoring |
St. Baldrick’s offers Summer Fellowship Awards, funding stipends for one undergraduate, graduate, or medical school student to work in a pediatric oncology research setting for a summer. The total award, paid to the mentor’s institution, is $5,000.
• Mentor and student pair is a prerequisite for applying.
• The mentor and student should work together on the application, but applications must be submitted with the mentor as Principal Investigator (PI) via ProposalCentral.
• Summer fellowship should last 8-10 weeks during summer. Preferred dates are between May and August.
• Students must currently be enrolled in an undergraduate, graduate, or medical degree program.
• Students may train at an institution other than their own institution.
• Institutions may submit only one (1) new Summer Fellow application per year. o Note: The limited submissions policy exception detailed in other program guidelines is not applicable for Summer Fellow awards.
• Mentor may apply only once per year in the Summer Fellow category. Applying for a Summer Fellowship does not affect eligibility to apply in other St. Baldrick’s funding categories.
• Mentor’s Institution must be located in the United States.
• Mentor and/or student need not be American citizens; however, the mentor must work at an academic, medical, or non-profit research institution within the United States.
• A program/institution is defined as an entity essentially operating under one management.
o Any questions or questionable situations will be reviewed by a subset of the Scientific Advisors of St. Baldrick’s. Questions can be emailed to Grants@Stbaldricks.org, please include a copy of the mentor’s biosketch.
• Institutions that are actively involved in (sponsor, promote, or participate in) non-St. Baldrick’s head-shaving fundraising events are not eligible to apply for St. Baldrick’s funding.
o St. Baldrick’s understands that hospitals and their fundraising agents and organizations cannot control what their many volunteers do. Some may undertake head-shaving fundraisers that hospital/agent/organization is not aware of and does not sanction or promote. These activities would not prevent the hospital’s researchers from applying for St. Baldrick’s grants.
o The following applies to hospitals, their fundraising agents and organizations as institutions. Researchers from hospitals would be ineligible to apply for St. Baldrick’s grants if the hospital/agent/organization promotes (advertises, emails, blogs, media stories, social media posts, shares, reshares, likes, tweets, re-tweets or hosts web pages) a non-St. Baldrick’s head-shaving fundraiser through any type of marketing, advertising, outreach or public-facing collateral or ancillary materials, or on any channel (television, radio, print, social media, website, etc.), using any content that sponsors, highlights, advocates or recommends a head-shaving event other than St. Baldrick’s.
• St. Baldrick’s funds may not be used for human embryonic stem cell research.
• No institutional overhead or indirect funding is provided under the terms of the grant. See Budget Guidance section for more details.
• Research projects must have direct applicability and relevance to pediatric cancer. They may be in any discipline of basic, clinical, translational, or epidemiological research.
• The mentor should currently hold an M.D./D.O., or Ph.D. degree and be working in the field of pediatric oncology research. • Summer Fellow must not have been a past awardee.
• The grant budget may include student salary/stipend, supplies, and other direct costs related to the summer fellowship expenses. Grant funds cannot be used for tuition. See Budget Guidance section for more details.
• All awards will be payable to the Mentor’s academic institution, non-profit research institution, or laboratory.
• All qualified applicants will receive consideration for funding without regard to race, color, ethnicity/national origin, sex, sexual orientation, gender identity or expression, pregnancy, religion, belief and spirituality, age disability status, protected veteran status, or any other characteristic protected by law.
Sponsor Institute/Organizations: St. Baldrick's Foundation
Sponsor Type: Corporate/Non-Profit
Address: 1333 South Mayflower Ave Suite 400 Monrovia CA 91016 Ph. (626) 792-8247 Grants@StBaldricks.org
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Feb 20, 2026
Feb 20, 2026
$5,000
Affiliation: St. Baldrick's Foundation
Address: 1333 South Mayflower Ave Suite 400 Monrovia CA 91016 Ph. (626) 792-8247 Grants@StBaldricks.org
Website URL: https://r1038-1.cdn.stbaldricks.org/file/sbf-summer-fellowship-guidelines.pdf
Disclaimer:It is mandatory that all applicants carry workplace liability insurance, e.g., https://www.protrip-world-liability.com (Erasmus students use this package and typically costs around 5 € per month - please check) in addition to health insurance when you join any of the onsite Trialect partnered fellowships.