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Research grant or fellowship projects

Prevent Cancer Foundation

The Prevent Cancer Foundation is supporting research grant or fellowship projects focused on cancers without guideline-recommended screening methods. By prioritizing these cancer types (for people at average risk), we seek to address a critical gap with potential for significant impact. Investing in research focused on cancer prevention, early detection, risk stratification and novel screening approaches for these cancers represents an opportunity to fundamentally change survival trajectories.

Application guidelines at a glance:

Applications must be innovative and demonstrate near-term potential for impact on cancer prevention and early detection.
We invite research applications that focus on the following cancer types:
- Blood (leukemia/lymphoma)
- Bone
- Brain (central nervous system)
- Esophageal
- Head-and-neck
- Liver
- Ovarian
- Pancreatic
- Sarcomas (connective-tissue)
- Stomach (gastric)
- Uterine
Applications focused on implementation science or population health that work with a specific community must include a Community Advisory Board component in the project.
Applicant institutions/organizations must be based in the United States. Applicants need not be United States citizens.
Research applications are limited to three submissions per institution. Institutions are defined by distinct EIN numbers.

Award amount

Grants will be awarded for two years at $50,000 per year, for a total of $100,000.

Timeline

Applications open: April 8, 2026
Program-specific office hours: April 23, 2026
ProposalCentral technical assistance office hours: May 15, 2026
Applications deadline: May 20, 2026, at 5:00 p.m. ET
Applicants notified of decisions: December 4, 2026
Awarded projects begin: January 15, 2027

AI Based Application Success Predictor

🧬 1. Strict Focus on Prevention & Early Detection (Non-Negotiable)

Core mission:
- Prevent cancer or detect it early
Funded areas include:
- Screening
- Risk prediction
- Vaccination and prevention strategies

👉 Treatment-only oncology projects → low success probability

🎯 2. Clear Impact on Reducing Cancer Incidence or Mortality (Top Predictor)

Successful proposals:

Demonstrate:
- Reduced cancer risk OR earlier diagnosis
Must show:
- Measurable population health benefit

👉 Key question:
“Will this help prevent cancer or detect it earlier?”

🔄 3. Translational & Implementation Focus (Critical)

Eligible projects include:
- Preclinical, translational, clinical, or implementation research
Strong preference for:
- Real-world applicability (clinical or community settings)

👉 Pure lab science without application is less competitive

🚀 4. Innovation in Screening & Risk Prediction

High success areas include:

Novel screening technologies
Risk prediction models
Behavioral interventions to improve screening uptake

👉 Innovation must be practical and scalable

🌍 5. Health Equity & Underserved Populations (Major Differentiator)

Strong emphasis on:
- Reducing disparities in cancer prevention and screening
Priority for:
- Medically underserved communities
- Rural populations

👉 Equity-focused proposals have a clear advantage

👥 6. Community Engagement & Real-World Implementation

Especially for community grants:
- Projects must:
  - Engage local populations
  - Include patient navigation or outreach

👉 Programs with community trust and partnerships score higher

👩‍🔬 7. Early-Career Investigator Development (Major Priority)

PCF strongly supports:
- Fellows and early-career researchers
Goal:
- Build next generation of prevention scientists

👉 Career development is a key evaluation factor

🧪 8. Feasible, Pilot-Scale Research (Seed Funding Model)

Grants are typically:
- ~$100K over 2 years
Designed to:
- Generate preliminary data

👉 Overly ambitious projects are often rejected

📈 9. Strong Potential for Future Funding & Impact

Explicit goal:
- Lead to larger external grants
Evidence:
- Awardees often secure significant follow-on funding and publications

👉 Projects with clear next-step funding pathways score higher

🧠 10. Broad Applicability Across Cancer Types

Funds multiple cancers:
- Breast, lung, cervical, colorectal, skin, etc.
Preference for:
- Approaches applicable across populations or cancer types

👉 Broader impact improves competitiveness

📊 Summary: Key Predictors (Ranked)

Highest impact factors:

Prevention/early detection focus
Measurable population impact
Translational/implementation pathway

Moderate predictors:
4. Innovation (screening, risk prediction)
5. Health equity relevance
6. Early-career development

Supporting factors:
7. Feasibility (pilot scale)
8. Community engagement
9. Future funding potential

💡 Insider Insight

Compared to other cancer funders:

Prevent Cancer Foundation is:
👉 prevention-first (not treatment-focused)
👉 strongly emphasizes real-world implementation + public health impact

👉 Winning formula:
Prevention/early detection idea + real-world application + measurable population benefit

✔️ What wins:

Screening innovations (especially accessible/low-cost)
Risk prediction models
Community-based prevention programs

❌ What struggles:

Treatment-focused oncology
Pure lab/basic research
Lack of population-level impact

Specialties

Cancer

Hematology

Orthopedics

Urology

Gastroenterology

Oncology

Pancreatology

Eligibility Requirements

Applications must fall within the scope of the Foundation’s mission and 2027 funding priorities to be considered. The issue of relevance to cancer prevention and/or early detection must be convincingly addressed in the application.

• The goal of the Foundation’s research program is to provide funding for innovative projects expected to lead to future funding from other peer-reviewed sources.

• All applications must be original and clearly describe innovative research projects in the field of cancer prevention and/or early detection. Projects that evaluate the potential for dissemination and implementation into clinical and community health settings are highly encouraged.

• All applications must demonstrate substantial near-term potential for impact on cancer prevention and/or early detection.

• Pre-clinical research with clear applicability to cancer prevention or early detection is acceptable, provided a translational relationship would be evident within five years. Applications are limited to three submissions per institution. Institutions may submit up to three applications for each Impact Grant track (research grants and fellowship projects and community projects). Institutions are defined by distinct EIN numbers.

• Applicant institutions/organizations must be based in the United States. Applicants need not be United States citizens.

• Applications focused on implementation science or population health that work with a specific community must include a Community Advisory Board component in the project.

Sponsor Details

Sponsor Institute/Organizations: Prevent Cancer Foundation

Sponsor Type: Corporate/Non-Profit

Address: 333 John Carlyle Street, Suite 635 Alexandria, VA 22314

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