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Project Grants in Clinical and Translational Medicine

Novo Nordisk Foundation

Purpose

Please note that text and guidelines are from 2025, new and updated guidelines will be available before next application round opens! The objective of this call is to broadly promote Danish clinical or translational research of high international level. The research should involve patients/humans and/or clinical practice, diagnostic or therapeutic methods, but can also involve established animal models.

Funding

A total of up to DKK 76 million is available for projects lasting from 1-3 years.

Projects of up to DKK 4,400,000 million can be applied for with a yearly maximum budget of DKK 1,480,000 million.

AI Based Application Success Predictor

🔬 1. Strong Alignment with Foundation Strategic Areas (Top Predictor)

NNF funding is highly aligned with its core priorities:

Biomedical & life sciences (major focus)
Cardiometabolic diseases (diabetes, obesity, cardiovascular)
Biotechnology & biosustainability
Global health & sustainability

👉 Projects outside these domains have very low success probability

🎯 2. Clear Scientific Excellence & Innovation

Successful proposals demonstrate:

High-impact, cutting-edge science
Novel hypotheses or technologies
Potential to advance fundamental understanding

👉 NNF is highly competitive and expects top-tier scientific quality

🌍 3. Demonstrated Societal & Health Impact (Critical Predictor)

Strong emphasis on:
- Improving human health
- Addressing global challenges (e.g., climate, health inequity)
Large grants require “impact upfront” planning and alignment

👉 Impact is explicitly built into evaluation frameworks

🔄 4. Translational & Innovation Potential

Preference for:
- Translational research (bench → application)
- Biotechnology innovation
- Solutions that can scale or be implemented

👉 Increasing focus on innovation ecosystems and real-world application

🤝 5. Strong Institutional & Collaborative Environment

High success rates are associated with:

Leading research institutions
International collaborations
Multi-disciplinary teams

👉 NNF frequently funds:

Research centres
Large collaborative programs

👩‍🔬 6. Investigator Excellence & Leadership Potential

Strong publication record
Proven research leadership (for large grants)
For early-career:
- Clear independence trajectory

👉 NNF funds both:

Elite senior scientists
Emerging “future leaders”

🧪 7. Feasible, Well-Structured Research Plan

Clearly defined:
- Objectives
- Methodology
- Milestones
Realistic timelines

👉 Large grants require highly structured project planning

📊 8. Ability to Build Research Capacity or Ecosystems

NNF strongly values:

Creation of:
- Research centres
- Infrastructure
- Innovation hubs
Long-term impact beyond a single project

👉 Funding often goes to ecosystem-building initiatives

🌐 9. Global & Strategic Relevance

Increasing support for:
- International collaborations
- LMIC-focused health initiatives
Expansion beyond Denmark

👉 Reflects global health and sustainability priorities

📑 10. Strong Proposal Communication

Clear articulation of:
- Innovation
- Impact
- Strategic relevance
Studies show effective “promotional framing” improves success rates

👉 Communication style influences reviewer perception

📊 Summary: Key Predictors (Ranked)

Highest impact factors:

Strategic alignment (life sciences, health, sustainability)
Scientific excellence & innovation
Societal/health impact

Moderate predictors:
4. Translational potential
5. Investigator strength
6. Collaboration & institutional quality

Supporting factors:
7. Feasibility & planning
8. Ecosystem-building potential
9. Proposal clarity

💡 Insider Insight

Compared to other funders:

Novo Nordisk Foundation is:
👉 science-driven like ERC/AACR
👉 but also impact- and innovation-focused like industry funders

👉 Key evaluation question:
“Will this research create significant scientific breakthroughs AND long-term societal impact?”

Specialties

Clinical Trials

Others

Eligibility Requirements

The research activities applied for must be anchored at a university, hospital or other non-profit research institution in Denmark.

Only principal investigators are eligible to apply.

Eligible Countries:

Denmark

Sponsor Details

Sponsor Institute/Organizations: Novo Nordisk Foundation

Sponsor Type: Corporate/Non-Profit

Address: Tuborg Havnevej 19 2900 Hellerup

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