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Funding Opportunity




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Postdoctoral Fellowship

Dravet Syndrome Foundation

Postdoctoral Fellowship Awards are designed to support early-career researchers under the mentorship of an independent investigator. These fellowships are awarded to qualified applicants whose proposed projects investigate hypotheses directly related to Dravet syndrome. Proposals are scored according to NIH guidelines based on the quality of preliminary data, research design, feasibility, investigator’s qualifications, and overall impact. Grants are awarded for $150,000 over 2 years (beginning January), intended to support a full-time research effort with salary and benefits (no indirect costs are allowed under this fellowship award). Award funds can also be allocated towards conference travel or support technology (such as a computer).

Applicants should ensure their proposed project addresses the needs of the Dravet syndrome community and DSF’s mission to support research toward better treatments and a cure for Dravet syndrome. DSF research funding priority areas are listed below.

Fellowship recipients are required to provide a final report upon completion and present their findings at our Research Roundtable meeting.

DSF Basic and Translational Priority Areas include:

  • Understanding the mechanisms of epileptogenesis in Dravet syndrome
  • Development of enhanced models to study Dravet syndrome
  • Understanding of the cellular, molecular, and genetic mechanisms that contribute to the pathogenesis of Dravet syndrome
  • Revealing causes and interventions for seizures and comorbidities in Dravet syndrome
  • Understanding causes and developing interventions for SUDEP
  • Development of novel treatments and interventions that will prevent the onset or halt the progression of Dravet syndrome; this includes research that may overcome the current size and delivery hurdles for gene-therapy approaches

DSF Clinical Priority Areas include:

  • Research that helps better characterize the natural history of Dravet syndrome across the patient lifetime, including identifying patient trends, characteristics, epidemiology, or other clinical aspects of Dravet syndrome and/or its comorbidities
  • Research that develops or refines outcome measurements that can fully reflect meaningful improvements in patient symptoms and quality of life
  • Research that helps to understand, predict, and prevent SUDEP
  • Research that will encourage the development of novel therapies to prevent onset or halt the progression of the Dravet syndrome

Applications are due Friday, August 21, 2026. 

AI Based Application Success Predictor

1. Direct Relevance to Dravet Syndrome (Strongest Predictor)

DSF explicitly states that funded projects must investigate hypotheses directly related to Dravet syndrome or associated epilepsies. Applications with only indirect relevance are unlikely to be competitive.

2. Novelty and Innovation

Research applications are judged principally on:

  • Novel hypotheses
  • Innovative approaches
  • New therapeutic concepts
  • Creative solutions to longstanding challenges in Dravet syndrome

Innovation is repeatedly highlighted as a primary review criterion.

3. Scientific Quality

Successful proposals typically demonstrate:

  • Rigorous methodology
  • Strong experimental design
  • Appropriate statistical planning
  • Clear milestones and endpoints

DSF uses a rigorous NIH-style review process and places substantial weight on scientific excellence.

4. Potential Impact on Patients

Competitive applications show how the work could:

  • Improve treatment options
  • Advance disease-modifying therapies
  • Reduce seizure burden
  • Improve quality of life
  • Address severe complications such as SUDEP (Sudden Unexpected Death in Epilepsy)

Projects with clear patient benefit receive strong consideration.

5. Alignment with DSF Priority Areas

Recent priority areas include:

  • Mechanisms of epileptogenesis
  • Cellular, molecular, and genetic mechanisms of disease
  • Improved disease models
  • Novel therapeutic approaches
  • SUDEP prediction and prevention
  • Natural-history studies
  • Outcome-measure development
  • Gene therapy and disease-modifying interventions

Applications matching these priorities are particularly competitive.

6. Feasibility and Likelihood of Success

DSF specifically evaluates the strength of approach and likelihood of success.

Successful applications generally include:

  • Realistic timelines
  • Achievable aims
  • Appropriate methodologies
  • Access to required resources and patient populations when relevant. 

7. Strong Preliminary Data

For larger mechanisms such as Transformational Science Grants, substantial preliminary data is specifically required and forms an important scoring criterion. Clinical Research Grants are also evaluated on the quality of preliminary evidence supporting the proposed work.

8. Translational and Clinical Potential

DSF prioritizes research with a clear path toward:

  • Clinical application
  • Therapeutic development
  • Genetic understanding
  • Disease modification

Projects that can move discoveries closer to patient care often score highly.

9. Investigator and Institutional Strength

Reviewers assess:

  • Investigator qualifications
  • Prior productivity
  • Relevant expertise
  • Institutional support
  • Research environment

For fellowships and clinician-researcher awards, mentor quality is also important.

10. Addressing Community Needs

A distinctive feature of DSF review is that final funding decisions consider not only scientific merit but also the priorities and needs of the patient community. Applications that address major unmet needs in Dravet syndrome may receive additional support.

Frequently Funded Research Themes

Recent DSF-funded projects commonly involve:

  • SCN1A biology and genetics
  • Gene therapy approaches
  • Disease-modifying therapies
  • Epileptogenesis mechanisms
  • Biomarker discovery
  • Natural-history studies
  • SUDEP prevention
  • Novel seizure interventions
  • Cellular and molecular disease mechanisms
  • Outcome measures and quality-of-life research

Successful applicants hold an MD, PhD, or equivalent degree, are a clinical or post-doctoral fellow at an academic institution, may be US or foreign based, and do not hold a higher level faculty appointment.

Sponsor Institute/Organizations: Dravet Syndrome Foundation

Sponsor Type: Corporate/Non-Profit

Address: PO Box 3026, Cherry Hill, NJ 08034 (203) 392-1955

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Grant, Fellowship

Letter Of Intent Deadline:

Aug 21, 2026

Final Deadline:

Aug 21, 2026

Funding Amount:

$150,000

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