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Medical Scientist Training Program

Mayo Foundation for Medical Education and Research

Mayo Clinic has made a continuing commitment to fully support the tuition and stipend costs for all M.D.-Ph.D. students throughout their medical and graduate training. This allows you to choose your thesis laboratory with a focus on the education and training you want to achieve.

Tuition

Mayo Clinic M.D.-Ph.D. Program students are fully supported (tuition and stipend) through a guaranteed internal fellowship for up to eight years contingent upon satisfactory progress in the program. This eliminates the need for students to identify a faculty member to provide financial support.

If additional funding is required for other student expenses, you have access to the resources of the Office of Student Financial Aid and Registrar.

Stipend

In addition to full tuition support, this guaranteed internal fellowship provides an annual graduate-level stipend. The 2025-2026 annual graduate-level stipend is $41,200 provided on a payment schedule.

Student benefits

Students are offered low-cost comprehensive medical insurance, including a prescription drug plan, as well as dental and vision insurance. Other student benefits include access to gym memberships, counseling services, and many more resources offered by our Office of Student Financial Aid and Registrar.

AI Based Application Success Predictor

Based on what is known from programs, published Mayo awardees, what Mayo requires, and internal peer norms, here are factors that tend to help internal Mayo grant applications succeed.

Predictor	What Strong Applications Usually Include / Do
Clear significance & alignment with Mayo’s mission & strategic priorities	Projects that clearly tie into clinical/translational research, patient care improvements, education excellence, population health etc. If your project has potential to influence Mayo’s core work (e.g. improving clinical outcomes, enhancing educational programs, etc.), that helps.
Well-defined aims, timeline, realistic scope	Because internal budgets are limited, proposals that are feasible, with clear deliverables, predictable timeline, manageable scope do better. If trying something new, pilot or proof of concept with realistic expectations tends to fare better.
Preliminary data or prior work	Even internal grants often expect some evidence you can accomplish what you propose: pilot data, prior relevant publications, evidence of ability to carry out similar work. This lowers risk in reviewers’ eyes.
Strong mentorship & institutional support	Having senior mentors, collaborators, access to cores / facilities; backing from department head; clarity that you have the environment needed to do the work. Also showing how the award helps your career development (for early career awards).
Protected research time	Especially for clinician scientists: clarity about how your clinical / service duties will be managed and that you’ll have sufficient time for the research. If that’s uncertain, it weakens the proposal.
New / innovative or change of direction	For certain awards (especially early career or enabling awards), proposals that introduce new ideas, or expand into new areas, or change direction, are valued — especially if the project is methodological or translational and opens new pathways.
Good writing, clarity, formatting, meeting all requirements	Common internal pitfalls are missing required sections, weak methods, overambitious budgets, unclear roles. Ensuring you meet all eligibility criteria, include mentor letters, define budget, etc., is essential.
Career outcomes & sustainability	Showing how the project will lead to further external funding, career advancement, publication, and will be sustained beyond the internal award. Reviewers tend to favor applications that think ahead.
Fit to the particular award’s purpose	Using the right award for your stage or purpose; for example, don’t apply to early-career if you’re mid-career, or to educational awards if your project is basic science; choose the scheme whose goals match your work.

Specialties

Clinical Trials

Others

Eligibility Requirements

Some of the main “must-haves” in Mayo’s intramural grants:

Appointment / rank requirements: Many internal grants require you to be Mayo Clinic faculty or in certain staff/research roles (e.g. “Associate Consultant”, “Senior Associate Consultant”, “Consultant”, Mayo Clinic Scholar, Research Associate, etc.) by certain dates.

Early vs Mid career: Some awards are specifically for early-career investigators; others for mid-career. The expectations differ (for example, early career might require more mentorship; mid-career expects some prior productivity).

Change of direction / new area viability: Some awards allow (or require) that you demonstrate a shift in research direction or that you will build novel capacity. For those, plan must describe how the funding will assist in that shift.

Mentorship & sponsor support: Mentor letters are often required; institutional support from department or division; showing that you have access to resources.

Restrictions on other funding: For example, for the KL2 and Early-Career Development Awards, you should not already have large equivalent NIH grants or be a PI on certain grants. Must meet NIH criteria for Early Stage Investigator in many cases.

Effort / protected time: Some clinician/scientist awards require that you commit a certain percentage of your time to research. For example, in KL2, certain specialties may be allowed less than full research time but not lower than some threshold; there needs to be clarity about time allocation.

Limitation on number of proposals / past awards: You can’t have repeatedly had certain Mayo internal award types beyond certain years; or you have limits for how many years one can get a particular program.

Sponsor Details

Sponsor Institute/Organizations: Mayo Foundation for Medical Education and Research

Sponsor Type: Corporate/Non-Profit

Address: 200 First St. SW Rochester, MN 55905

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