LYMPHOMA RESEARCH FOUNDATION OVERVIEW: The Lymphoma Research Foundation remains dedicated to finding a cure for lymphoma through an innovative research program and by supporting the next generation of lymphoma researchers. LRF provides education for people with lymphoma, their loved ones and caregivers, including comprehensive disease guides and facts sheets, in-person conferences and online resources. The Foundation also provides continuing medical education programs designed to increase the knowledge, skills and performance of healthcare professionals. The Foundation’s support services, including the LRF Helpline, Clinical Trials Information Service, financial assistance programs and Lymphoma Support Network, provide direct support to people with lymphoma. To learn more about the Foundation, visit lymphoma.org.
LYMPHOMA SCIENTIFIC RESEARCH MENTORING PROGRAM OVERVIEW: The Lymphoma Research Foundation Lymphoma Scientific Research Mentoring Program (LSRMP) is an education and mentoring program with two tracks: the Clinical Track, for clinical fellows and junior faculty with a focus in clinical research in the field of lymphoma, including epidemiology, and the Laboratory/Translational Track, for researchers at the levels of postdoctoral fellow, clinical fellow, or junior faculty with an interest in laboratory-based research including, bench, translational and pathology research as well as statistical research.
The Foundation considers “lymphoma” to encompass all lymphoma subtypes, as well as chronic lymphocytic leukemia (CLL). The program is two years in length and offers a broad education on research and career development as well as managing career and quality of life issues. The goals of the LSRMP include:
• Provide mentoring and education to clinical fellows, postdoctoral fellows and junior faculty interested in lymphoma/CLL research. The program will emphasize training in scientific research methods and design, statistical analysis, pathology, incorporating and interpreting correlative studies into clinical trials, and grant submission and funding. The program also aims to foster mentorship and research collaboration among experts and trainees in the field.
• Assist in the development of a research project relevant to lymphoma which will set the foundation for grant development. For Clinical Track applicants, this should be a clinical trial or study that directly involves patients; Laboratory/Translational Track applicants may propose any laboratory, or translational research project that will advance current understanding of lymphoma biology, prognosis/diagnosis, or outcomes. Project design and implementation will be discussed in a small group setting consisting of experts in the field, statisticians, and other trainees in the program, where information, ideas, guidance, support and connections are shared, and where mentoring relationships can be developed.
• Provide continuing training, career development advice, and mentorship among trainees and experts in the field and to foster future participation and collaboration within the Lymphoma Research Foundation through follow-up programming and activities.
The Lymphoma Research Foundation (LRF) is renowned for its reputation as the largest nonprofit fully devoted to lymphoma and CLL research. Its structured, career-stage–focused funding model—combined with rigorous peer review and mentorship—has consistently cultivated future leaders in the field. Here’s how:
1. Targeted Career Development Grants
LRF’s grant programs are designed to propel investigators from early stages to independence:
Postdoctoral Fellowship Grants: Award approximately $195,000 over three years for early-stage scientists (MD or PhD). These grants provide research salary and support, enabling focused, foundational lymphoma research.
Clinical Investigator Career Development Awards (CDA): Designed for advanced fellows or early junior faculty, offering salary, protected research time, and research expenses over three years. This award often represents a researcher's first significant independent funding.
Lymphoma Scientific Research Mentoring Program (LSRMP): A unique initiative combining hands-on mentoring, workshops, and networking. Participants (LRF Scholars) receive a $10,000 professional development grant and mentorship to strengthen future success.
Disease Focus Area Grants: Support mid-career researchers tackling specific lymphoma subtypes or populations—acting as bridge or competitive R01-style grants to facilitate larger funding.
2. Strong Success Rates
Between 2020–2024, the LRF averaged notable success rates across its early-career programs:
Clinical Investigator CDA: ~32% funding rate
Postdoctoral Fellowships: ~35%
LSRMP—Clinical Track: ~48%
LSRMP—Translational Track: ~61%
These figures underscore the foundation’s commitment to supporting promising researchers.
3. Proven Impact & Breakthroughs
LRF’s investments have directly led to some pivotal advances:
First human trials of adoptive immunotherapy in follicular lymphoma
Whole-genome sequencing of mantle cell lymphoma
Elucidation of RNA splicing roles in CLL
Discovery of biomarkers tied to mantle cell lymphoma drug resistance
Understanding mechanisms of ibrutinib resistance
4. Cultivating Talent & Visibility
In 2024 and 2025, LRF awarded many early-career researchers:
2024: 28 grants, $3.5M across institutions, supporting research into genetic mechanisms and novel treatments.
2025: 24 grants totaling $2.7M—including both CDA and postdoc fellowships—covering areas like CAR T-cell therapy and microenvironment studies.
These awardees receive spotlight features (“Researcher Spotlights”), enhancing recognition and opportunities for collaboration.
5. Real-World Traction: Success Story Example
Elisa Oricchio, a LRF Fellowship awardee, identified that the EphA7 tumor suppressor is frequently lost in follicular lymphoma. Her foundational discovery, supported by LRF, propelled her to prestigious institutional roles—becoming a tenured assistant professor and later securing an endowed chair in Translational Oncology at EPFL.
Summary Table: How LRF Grants Predict Career Success
| Program / Grant | Stage | Predictive Value |
|---|---|---|
| Postdoctoral Fellowship | Early-career | Enables focused research, builds publication record |
| Clinical Investigator CDA | Early faculty | Launches independent clinical careers |
| LSRMP (Mentoring Program) | Mentorship & funding | Builds skills, network, and grant readiness |
| Disease Focus Area Grants | Mid-career | Catalyzes subtype-specific breakthroughs |
| Track Record of Impact | Across career stages | Leading to translational oncology advances |
The Lymphoma Research Foundation serves as a reliable predictor of success. Its tiered grants not only provide critical early funding but also deliver mentorship, visibility, and institutional credibility—key ingredients for launching impactful careers in lymphoma research.
1. Applicants must demonstrate a clear interest and commitment to a career in lymphoma clinical research. This commitment to a career focused on lymphoma-related research should be reflected in the applicant’s career development plan and in the letter of support provided by their mentor.
2. Applicants for this track must be one of the following, with requirements calculated per the applicant’s status as of March 1, 2026:
a. a junior faculty member with an MD or equivalent degree in their first five years holding a faculty position. Eligible titles include, but are not limited to, Instructor, Clinical Instructor, Assistant Professor and Clinical Assistant Professor.
b. a clinical fellow who is at least in their second year of one of the following ACGME accredited sub-specialty fellowship programs: Hematology/Oncology, Hematology, Medical Oncology, Radiation Oncology, Pediatric Hematology/Oncology, or Hematopathology. Pathology fellows in one-year fellowship programs and applicants from other clinical sub-specialties will be considered based on the application’s description of the relevance of the research and career development plan to lymphoma, please contact researchgrants@lymphoma.org for eligibility review.
3. Applicants should not be more than five years beyond completion of their fellowship or more than thirteen years beyond completion of their MD or equivalent degree as of March 1, 2026.
4. Applicants must be affiliated with a sponsoring academic or nonprofit research institution in the U.S. or Canada for the duration of the LSRMP award. Citizenship is not required. LSRMP awards are open to applicants from the NIH or other U.S. government entities.
5. Applicants should not be participating in another competitively applied for mentorship (such as ASH’s CRTI) during the LSRMP period (March 2026 through October 2028). Applicants who will have completed other mentorship programs prior to March 2026 are welcome.
6. Selected applicants are required to attend and participate in all LSRMP programs in their entirety including the 2026 workshop, follow-up programs (Fall 2026 and 2027), and Foundation required communication, reporting, and evaluation. 7. Fluency in English.
8. Studies or proposals that are exclusively laboratory based are not appropriate for the Clinical Track, please see Laboratory/Translational track eligibility below. Proposals must involve clinical observation of human subjects and may include study or development of new diagnostic methods, therapies, and/or outcome measurements directed to patients with lymphoma. Epidemiology projects are included in this track.
9. All applicants must have an identified primary mentor at their home institution who is willing and able to provide financial support for the project and demonstrate a commitment to completing the proposal in order to ensure feasibility of the proposal. Associate mentors, who may provide support for additional aspects of the project and be based at other institutions, are welcome but not a requirement.
10. LSRMP applications are self-initiated. The Lymphoma Research Foundation does not invite applications from selected individuals, institutions, or laboratories.
Sponsor Institute/Organizations: Lymphoma Research Foundation
Sponsor Type: Corporate/Non-Profit
Address: Wall Street Plaza 88 Pine Street, Suite 2400 New York, NY 10005
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Sep 04, 2025
Sep 04, 2025
$10,000
Affiliation: Lymphoma Research Foundation
Address: Wall Street Plaza 88 Pine Street, Suite 2400 New York, NY 10005
Website URL: https://lymphoma.org/wp-content/uploads/2025/07/FY2026-LSRMP-RFP-updated.pdf
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