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Lobular Breast Cancer Alliance Invasive Lobular Carcinoma Innovation and Discovery Grants

Lobular Breast Cancer Alliance

Description

Invasive lobular carcinoma (ILC), also known as lobular breast cancer, is the second most common histological subtype of breast cancer. ILC has a unique biology and a distinct clinical pattern of behavior and is a challenging disease entity in terms of diagnostics, staging, and therapeutic options. There is a critical need to advance understanding of this disease and improve treatment and follow-up care options for patients living with ILC.

The AACR-Lobular Breast Cancer Alliance Invasive Lobular Carcinoma Innovation and Discovery Grants is a joint effort to stimulate and develop creative, paradigm-shifting ideas in ILC research to ultimately contribute to development of new treatment options that may not be funded through conventional channels.

Applications are invited from researchers who have studied ILC as well as investigators with experience in other areas of cancer or biomedical research.

Each grant provides $50,000 over one year for expenses related to the research project. Grant funds may be used for direct research expenses attributable to the project, which may include supplemental salary support, equipment, research/laboratory supplies, and other research expenses. Up to 5% of grant funds may be used on indirect costs.

Program Guidelines

Program Guidelines and Application Instructions are available for download. Please read all eligibility criteria and instructions carefully before submitting an application.

Research Project Criteria

These grants are intended to support projects focused on invasive lobular carcinoma (ILC). Applications in any aspect of clinical or basic research directly related to lobular breast cancer will be considered. Research proposals should focus on biology, diagnosis, treatment and/or prevention of lobular breast cancer or its metastases.

Citizenship Requirements

There are no citizenship or geographic requirements. However, by submitting an application for this grant, an applicant applying from an institution located in a country in which they are not a citizen or a permanent resident assures that the visa status will provide sufficient time to complete the project and grant term at the institution from which they applied.

AI Based Application Success Predictor

LBCA itself does not publish a unified “success predictor” scoring rubric the way federal agencies do. However, based on its partnered grant programs and solicitations, the following are key factors that influence competitiveness and funding success:

✔ Alignment With ILC Focus

Proposals must be directly relevant to invasive lobular carcinoma or metastatic ILC — including research on biology, diagnostics, treatment, or prevention.

✔ Research Merit & Innovation

Grants like the AACR-LBCA Innovation & Discovery award aim to stimulate creative, novel approaches that might not be funded through conventional mechanisms.

✔ Career Stage Goals

Career development awards focus on early-career investigators with promising research plans in ILC, so the investigator’s potential and track record matter.

✔ Peer Review or Scientific Evaluation

Collaborative grants (e.g., with AACR/BCRF or Conquer Cancer/ASCO) are administered through established scientific review panels using criteria such as innovation, feasibility, and impact on lobular breast cancer outcomes — even if detailed scoring rubrics aren’t publicly posted.

✔ Proposal Clarity & Relevance

Strong, well-described research plans that clearly address unmet needs in ILC detection, biology, treatment, or metastasis tend to be more competitive.

📌 In Summary

The Lobular Breast Cancer Alliance (LBCA) actively collaborates with major cancer research funders like AACR, BCRF, ASCO/Conquer Cancer, and Susan G. Komen to fund ILC-focused research grants spanning innovation awards, career development support, and metastatic cancer research.

LBCA’s grant opportunities are designed to support novel ideas and early-career investigators and address significant gaps in invasive lobular carcinoma science.

There is no single formal success predictor model published by LBCA, but competitiveness is shaped by:

Direct relevance to ILC research

Scientific innovation and clarity of proposal

Investigator potential and career focus

Alignment with partnered funder priorities.

Specialties

Cancer

Oncology

Gynecology

Eligibility Requirements

Applicants must have a doctoral degree (PhD, MD, MD/PhD, or equivalent) in a related field and not currently be a candidate for a further doctoral degree or equivalent.

At the start of the grant term on July 1, 2026, applicants must:

Be independent investigators and be affiliated with an academic, medical, or non-profit research institution.
- If eligibility is based on a future position, the position must be confirmed at the time of application andCANNOTbe contingent upon receiving this grant.
- If the future position is at a different institution than the applicant’s current institution, the applicant must contact AACR’s Research and Grants Administration Department (AACR’s RGA) at grants@aacr.org before submitting their application for information on additional verification materials/signatures that may be required.
Work at an academic, medical, or research institution anywhere in the world.

Sponsor Details

Sponsor Institute/Organizations: Lobular Breast Cancer Alliance

Sponsor Type: Corporate/Non-Profit

Address: 615 Chestnut St., 17th Floor Philadelphia, PA 19106-4404

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