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Funding Opportunity




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E.W. "Al" Thrasher Awards

Thrasher Research Fund

Award Focus

E.W. "Al" Thrasher Awards focus on projects that are changing pediatric clinical care. Each award is a novel approach to problems plaguing pediatrics. The award is open to applications focusing on any disease or topic within the umbrella of pediatrics, both in and outside the United States.  

Ideal applications for the Thrasher Award address significant health problems, offering the potential for practical solutions to these problems. Typically, the primary outcome is a health outcome in children. Solutions should be innovative and have the potential for broad applicability with low barriers to implementation. Projects with a shorter distance to clinical applicability are given priority.​ Hypothesis-driven research is critical, exploratory, or hypothesis-generating research will not be competitive. 

For projects focused on improving disease diagnosis, please ensure that there are well researched, effective treatment options available to patients upon diagnosis.

Exclusions

  • Behavioral science research including classes or counseling on health habits, treatments, stress coping, or mental health
  • Educational programs including training for patients, caregivers, or hospital staff
  • Projects focusing solely on disease mechanism or microbiome
  • Research on human fetal tissue
  • Research conducted in cell lines or animal models

Application Tips and Requirements

Thrasher's focus is on child outcomes- we want to fund science that will make meaningful progress in the way diseases are diagnosed and treated. Competitive grants often, but are not required to, focus on severe or high incidence diseases. The aims include child driven outcomes, and the proposals are far enough along in the research process to make a clinical difference within a few years. 

If the submitted grant includes study sites outside the Principal Investigator home country, applications must include a co-investigator from each country included as a study site. Capacity building and buy in from local leaders and clinicians is critical to our mission for improving child health. 

Please feel free to reach out to out Research Managers with inquiries about project ideas or proposal aims. We are happy to discuss specifics and give you an idea of what will be competitive. 

Application Process

The Fund uses a two-step process for E.W. "Al" Thrasher Awards. The first step is the submission of a Concept Paper. These Concept Papers are reviewed by the Fund's staff. Applicants whose concepts generally fit with the current priorities of the Fund are invited to submit a full proposal. Applicants have about 10 weeks to submit a full proposal from the date of invitation. Full proposals are reviewed by external peer reviewers with specific expertise in the subject being proposed. Proposals recommended by peer reviewers are considered by the Fund's Committees. The Committees meet to make funding decisions in March and September.

Budget Guidelines

The grant amount is based on the actual budgetary needs of the project. The duration of the project can be up to three years. Indirect costs are no more than 7% of direct costs. In 2020-2025 the median grant was $420,000. Grants are generally not given over $600,000.

Investigators and co-investigators in need of salary support may apply for no more than 20 percent, based on a 40-hour work week. The Fund limits the maximum salary upon which an individual can request salary support. The maximum amount will be based on the NIH guidelines for salary support. Salaries for support staff, students, and others do not have the 20% restriction.

Requests for purchase of major equipment (items >$4,000) are discouraged and rarely funded.

The final budget should be consistent with the budget amount proposed in the approved Concept Paper.  All exceptions must be cleared through the Fund.


AI Based Application Success Predictor

1. Direct impact on children's health (highest predictor)

This is the single strongest predictor.

The Fund does not focus on any specific disease area, but every funded project must deal directly with child health and have the potential to improve outcomes for children.

Strong topics include:

  • Pediatric infectious diseases
  • Neonatal medicine
  • Childhood nutrition
  • Pediatric neurology
  • Childhood cancer
  • Pediatric pulmonary diseases
  • Global child health
  • Genetic disorders in children
  • Child health implementation research

2. Clear pathway to clinical impact (very high predictor)

A defining characteristic of Thrasher is its preference for projects with a realistic path toward improving clinical care.

The Fund has explicitly stated that it prioritizes:

  • Clinical pediatric research
  • Near-term clinical translation
  • Practical solutions to important pediatric health problems

Projects focused primarily on biological mechanisms without a clear clinical application are generally less competitive.

3. Important pediatric health problem with meaningful unmet need (very high predictor)

Reviewers evaluate:

  • Disease severity
  • Disease burden
  • Incidence/prevalence
  • Availability of current treatments
  • Barriers to implementation

Applications addressing serious pediatric conditions with insufficient existing solutions are particularly attractive.

4. High-quality hypothesis-driven science

The Fund specifically supports:

"clinical, hypothesis-driven research"

Successful applications typically demonstrate:

  • Clear research hypothesis
  • Strong rationale
  • Appropriate study design
  • Statistical rigor
  • Feasible methodology

Scientific quality remains a major determinant of success.

5. Strong potential for future independent funding

Both major funding mechanisms are intended to build future research careers.

For Early Career Awards, the stated goal is to support investigators who will become independent researchers.

Competitive projects often:

  • Generate preliminary data
  • Establish new pediatric research programs
  • Lead to NIH, Wellcome, MRC, CIHR, or equivalent funding

6. Outstanding mentor and mentoring plan (especially important for Early Career Awards)

One of the few foundations that explicitly highlights mentorship as a major predictor.

The Fund states that:

  • Mentor quality
  • Mentoring relationship
  • Mentor track record
  • Prior collaboration between mentor and applicant

are important factors in funding decisions.

For Early Career Awards, a strong mentor can significantly increase competitiveness.

7. Investigator aptitude and research trajectory

For Early Career Awards, Thrasher evaluates the applicant's:

  • Research aptitude
  • Long-term commitment to child-health research
  • Publication record relative to career stage
  • Prior awards and recognitions
  • Role in developing the project

The program is designed to identify future leaders in pediatric research.

8. Feasibility and realistic implementation

Reviewers favor projects with:

  • Achievable aims
  • Realistic recruitment plans
  • Appropriate budget
  • Clearly defined milestones
  • Practical implementation strategy

Projects must demonstrate a credible path to completion and clinical relevance.

9. Broad applicability of findings

The Fund has historically favored research that can produce findings applicable beyond a single institution or narrow patient population.

Projects with potential to influence broader pediatric practice, guidelines, or public health tend to align strongly with Thrasher priorities.

Principal Investigators must be qualified in terms of education and experience to conduct research. A doctoral-level degree is required. There are no citizenship or residency requirements. The Fund is open to applications from institutions both inside and outside the United States.

Sponsor Institute/Organizations: Thrasher Research Fund

Sponsor Type: Corporate/Non-Profit

Address: 68 S. Main Street, Suite 400 Salt Lake City, UT 84101

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Grant

Letter Of Intent Deadline:

Jul 14, 2026

Final Deadline:

Jul 14, 2026

Funding Amount:

$420,000

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