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Dr. Charles A. Coltman, Jr. Fellowship Program

Hope Foundation for Cancer Research

The SWOG Cancer Research Network Dr. Charles A. Coltman, Jr. Fellowship Program protects time for clinical or translational research on SWOG-associated projects. The funding encourages investigators from SWOG member institutions to engage either in learning clinical trial methodology or in expanding current research interests within a cooperative group environment. The program strives to honor the legacy of long time SWOG Chair and leader, Dr. Chuck Coltman, through encouraging the spirit of scientific integrity and the ultimate commitment to bettering patient care.

The Hope Foundation for Cancer Research sponsors the Coltman Fellowship Program through support of early career awards. Each award provides $100,000 over two years to successful candidates, as well as key travel support.

Award Payments

The fellowship provides $100,000 over two years, to be paid at $50,000 per year. Payment will be presented annually to the designated financial officer of sponsoring institution. Second year payments are contingent upon submission/approval of progress and financial reports. Additional travel support will be available from the Foundation for each Fellow.

A Fellow may request in writing to pay the balance forward to year two. The release of funds for the second year is dependent upon receiving the progress report and its approval by SWOG/THF.

No Indirect Cost is paid on this award.

AI Based Application Success Predictor

1. Strong Scientific Significance & Relevance

The most critical driver of success is proposing research that addresses important problems in cancer detection, treatment, control, or prevention — especially those aligned with SWOG’s mission of improving clinical cancer outcomes. Projects should show a clear rationale that the research will meaningfully advance understanding or clinical practice.

📌 What reviewers look for:

Clear definition of a critical barrier in cancer research

Demonstrated potential to advance cancer science or care

Relevance either to clinical trials or translational pathways

2. Innovation & Novelty

A core review criterion across Hope Foundation-funded mechanisms (including SEED and Impact Awards) is innovation — proposing ideas or methods that go beyond routine incremental research. Projects that could challenge current paradigms or open new avenues for research tend to score higher.

📌 What this means in practice:

Novel therapeutic approaches, biomarkers, or trial designs

Methods that could enable future clinical trials

Early exploratory research with potential for translational impact

3. Investigator Qualifications & Team Strength

Review panels assess whether the PI and collaborators have the experience, expertise, and track record to execute the project successfully. This includes evidence of relevant publications, prior research accomplishments, and complementary skills within the team.

📌 Positive signals include:

Established research record in oncology (clinical, translational, or methodological)

Prior involvement in cooperative group (SWOG) research

Experienced collaborators, particularly when projects are interdisciplinary

4. Strong Research Approach & Feasibility

Reviewers evaluate the conceptual framework, study design, methods, and analytical plan in a manner closely aligned with NIH peer review criteria (significance, innovation, approach, investigators, and environment). A well-reasoned approach with realistic milestones increases the likelihood of success.

📌 Key success factors:

Well justified methods appropriate to the aims

Consideration of alternative strategies and risk management

Evidence that the study can be completed in the proposed timeframe

5. Appropriate Research Environment & Institutional Support

Grants from Hope Foundation mechanisms consider whether the institution where the research will be conducted provides a supportive and high-quality environment — including access to necessary resources, infrastructure, and collaborators.

📌 Environmental indicators of success:

Strong mentorship (especially for early career researchers)

Laboratory or clinical resources appropriate to the project

Institutional commitment to the research area

6. Alignment with SWOG’s Mission (for SWOG/Hope Awards)

Many Hope Foundation awards (e.g., SEED, Impact Awards) specifically fund research that will inform future SWOG clinical trials or derive value from completed SWOG studies. Projects that clearly support SWOG’s network goals in cancer clinical trials are especially competitive.

📌 What this looks like:

Secondary analyses of SWOG clinical trial data

Exploratory translational studies directly tied to future trial concepts

Research designed to strengthen SWOG committee portfolios

🧠 Additional Practical Insights

A. Early/Exploratory Projects with Potential for Future Funding

Programs such as the SWOG Early Exploration & Development (SEED) Fund encourage pilot or early-stage work that can lead to larger extramural research grants. Demonstrating that your project is a strong stepping stone toward broader funding increases competitiveness.

B. Clear Research Impact and Translation Pathway

Even high-risk or exploratory projects succeed more when applicants can articulate how the outcomes might directly inform clinical practice, future trials, or broader cancer research goals — especially when traditional funding might not yet support the idea.

📌 Summary of Top Predictors of Success

Predictor	Why it Matters
Clear scientific significance	Demonstrates direct impact on cancer science or care
Innovation & risk-taking	Signals potential for breakthroughs
Strong investigator/team profile	Builds confidence in execution and publication
Sound methods & feasibility	Ensures project can be completed as proposed
Supportive research environment	Provides infrastructure and mentorship
Alignment with SWOG mission	Enhances relevance to Hope Foundation priorities

Specialties

Clinical Trials

Eligibility Requirements

The applicant must hold an early career faculty appointment at a SWOG member institution (Assistant Professor, Clinical Instructor, Lecturer) or demonstrate 0-7 years of experience in clinical research (e.g., having held a leadership/key position on a protocol development team, or having independently developed a protocol).

If there are questions regarding whether the potential applicant is at the correct career stage, applicants are encouraged to send an email to jo@thehopefoundation.org for clarification and eligibility verification.

The candidate must also name a Primary Mentor. Appropriate mentors are active in SWOG as Principal Investigators and/or Committee Chairs, Vice Chairs, or contributing members. Mentors are required to attend the SWOG meeting at least once a year. A mentoring plan is required.

Other eligibility requirements:

• Candidates must have a minimum of 25% protected time for clinical/translational research.

• Candidates with active multi-year career development awards (i.e.: K-award, ACS, DOD) are not eligible.

• The applicant must be a member of SWOG and at a SWOG member institution at the time of grant award.

• International applicants from SWOG institutions are welcome to apply.

Sponsor Details

Sponsor Institute/Organizations: Hope Foundation for Cancer Research

Sponsor Type: Corporate/Non-Profit

Address: 24 Frank Lloyd Wright Drive P.O. Box 483 (Suite 4300K) Ann Arbor, Michigan 48105

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