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NOIP: Consortia for Structure-based Immunogen Design for HIV (CSID-HIV)

National Institutes of Health

Note: This is a Forecasted Opportunity.

The National Institute of Allergy and Infectious Diseases (NIAID) seeks to advance the National Institutes of Health (NIH) mission by supporting research to support structure-based immunogen design to advance the development and selection of HIV immunogens that induce broadly neutralizing antibody (bNAb) responses. These immunogens will then be advanced into clinical testing. Consortium research should address critical immunogen design roadblocks in discovering and developing safe and effective HIV bNAbs and bNAb responses that can be used as therapeutics, as well as guide vaccine development that could be used for both HIV treatment and prevention. This notice of funding opportunity (NOFO) will support coordinated multidisciplinary efforts on bNAb and vaccine discovery and applied research, emphasizing iterative approaches to expedite HIV therapeutics and vaccine development. The ultimate goal is to achieve proof of concept of therapeutic strategies using bNABs and vaccine-induction of bNAbs targeting multiple bNAb sites, while also integrating other cooperative immune responses. The technology being developed through these consortia will be applicable to other fields facing significant hurdles in viral antigen therapeutic targeting and vaccine design.

Estimated Post Date:

Feb 12, 2026

Estimated Application Due Date:

Apr 14, 2026

Specialties

Interdisciplinary

Medical - Basic Science

Medical

Medical - Translational

Eligibility Requirements

Sponsor Details

Sponsor Institute/Organizations: National Institutes of Health

Sponsor Type: Government/Federal

Address: National Institutes of Health; 31 Center Drive; MSC 2220; Bethesda; MD 20892-2220; USA

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