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Heart Transplantation Research Network Planning Grant

American Heart Association

The American Heart Association announces a Request for Proposals (RFP) for a planning grant opportunity through its Heart Transplantation Research Network.

This Request for Proposals seeks applications from qualified research institutions that can participate in planning grants for clinical trials in immune tolerance, chronic rejection, prevention of infection or the development of malignancy for adults or pediatric patients. Comprehensive trials that seek to identify predictive biomarkers or surrogate endpoints may also be considered.

This Request for Proposals is designed to provide support for the development of a detailed trial protocol and grant to be submitted to a federal agency or other major funder focused on developing and testing ways in which diagnostic or therapeutic interventions can improve health outcomes. Investigators funded through this RFP will be provided with salary and other support over the course of 12 months to:

Optimize and finalize trial design;
Draft a grant proposal to a federal agency or other major funder;
Finalize a protocol and manual of procedures;
Establish a research team;
Develop tools for data management and research oversight;
Prepare other items needed for the submission and conduct of a rigorous trial to address therapeutic and management gaps in heart transplantation, including any preparatory steps for IND submission if required.
If needed, a regulatory strategy must be included.

The primary deliverable at the end of this grant period should be a rigorous and highly competitive proposal for funding of >$3M to include federal and related agencies (NIH, PCORI, ARPA-H, USDA, and others) or state agencies. Proposals for industry or foundation support may also be submitted, but the planning grant proposal should provide justification for such sources of support.

Proposal deadline: Dec. 15, 2026

Specialties

Medical

Medical - Clinical Science

Medical - Basic Science

Medical - Translational

Eligibility Requirements

Heart Association research awards are limited to U.S.-based non-profit institutions, including medical, osteopathic, and dental schools, veterinary schools, schools of public health, pharmacy schools, nursing schools, universities and colleges, public and voluntary hospitals and others that can demonstrate the ability to conduct the proposed research.

Sponsor Details

Sponsor Institute/Organizations: American Heart Association

Sponsor Type:

Address: 7272 Greenville Ave. Dallas, TX 75231

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