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Animal and Biological Material Resource Centers (P40) (Clinical Trials Not Allowed)

National Institutes of Health

This Notice of Funding Opportunity (NOFO) encourages grant applications for Animal and Biological Material Resource Centers. These Centers provide support for special colonies of laboratory animals and associated services, as well as other resources such as informatics tools, reagents, cultures (cells, tissues, and organs) and genetic stocks that serve the biomedical research community in a variety of research areas on a local, regional, and national basis. The goal of projects supported by this NOFO is to provide research resources that facilitate optimization and enhancement of scientific rigor, transparency, and experimental reproducibility of biomedical research. Proposed Animal and Biological Material Resource Centers must have broad application to multiple NIH Institutes or Centers (ICs) to align with the ORIP’s NIH-wide mission ( https://orip.nih.gov/about-orip ). This funding opportunity is designed to support both continuation of existing resources and to develop new ones when appropriate. Of special interest of the announcement is a requirement of the Center’s close coordination with efforts to develop new approach methodologies (NAMs) that complement traditional animal-based research. These include cell culture, organoids, computational models, and microphysiological systems. Applied Research Component should include studies to generate comparative data to increase applicability of NAMs and promote integration of the most predictive human disease models. Prior to preparing an application, all applicants are strongly encouraged to consult with Scientific/Research staff to be advised on appropriateness of the intended resource plans for this program, competitiveness of a potential application, and ORIP's program priorities.

Deadlines:

Application Due Date(s): Feb 18, 2026; May 27, 2026; Sep 21, 2026; Jan 26, 2027; May 28, 2027; Sep 28, 2027; Jan 31, 2028; May 30, 2028; Sep 26, 2028
AIDS Due Dates: May 11, 2026; Sep 9, 2026; Jan 11, 2027; May 10, 2027; Sep 8, 2027; Jan 10, 2028; May 9, 2028; Sep 11, 2028; Jan 9, 2029

RFA-OD-25-011 Expiration Date January 10, 2029

Specialties

Environmental & Life Sciences

Medical - Basic Science

Medical

Medical - Clinical Science

Eligibility Requirements

Sponsor Details

Sponsor Institute/Organizations: National Institutes of Health

Sponsor Type: Government/Federal

Address: National Institutes of Health; 31 Center Drive; MSC 2220; Bethesda; MD 20892-2220; USA

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