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Accelerating Cryo-ET Through Improved Vitrification and Monitoring RFA

Chan Zuckerberg Initiative

Biohub invites applications for two-year research projects to accelerate advances in cryo-electron tomography (cryo-ET) by supporting the development of innovative vitrification methods and real-time monitoring technologies that improve the consistency, efficiency, and scalability of sample preparation of cells and tissues.

Deadline: July 16, 2026

Specialties

Engineering and Physical Sciences

Medical

Medical - Translational

Interdisciplinary

Medical - Basic Science

Eligibility Requirements

Applications may be submitted by domestic and foreign nonprofit and for-profit organizations, public and private institutions, such as colleges, universities, hospitals, laboratories, units of state and local government, companies, and eligible agencies of the federal government. As part of the application process, for-profit organizations may need to provide additional information on the charitable purposes of the proposal. Grants are not permitted to individuals, only to organizations.
An organization may submit more than one application.
Each application should designate one Principal Investigator (PI) as the Coordinating Principal Investigator (Coordinating PI). The Coordinating PI will act as the administrative contact between Biohub and all PIs on the grant. The Coordinating PI must submit the application on behalf of all PIs. The Coordinating PI must be affiliated with the institution submitting the application, and grant funds will be awarded to that institution, which will take responsibility for distributing funds to any other institutions. Note that institutions outside the U.S. may not subcontract to U.S. institutions, so please be mindful when selecting the Coordinating PI/institution.
Each application should have a minimum of one PI (Coordinating PI), but may designate up to three total PIs (one Coordinating PI and up to two Co-PIs).
PIs may only serve as the Coordinating PI on one application, but may serve as a Co-PI on applications different from the one they submitted.
Co-PIs may serve as a Co-PI on multiple applications.
PIs/Co-PIs on one application may be employed at the same or at different institutions.
PIs and Co-PIs must hold a PhD, MD, or equivalent degree.
PIs and Co-PIs must each run laboratories in which they control their budget, their space, and their research. Independence in an academic setting is typically demonstrated by a full-time faculty appointment, a tenure-track position, allocated space, a start-up package, and institutional commitment as defined or verified in a letter from a department chair or equivalent. Independence may be defined differently in other organizations. Note: an upload of the letter or proof of independence is not required at the time of application.

Sponsor Details

Sponsor Institute/Organizations: Chan Zuckerberg Initiative

Sponsor Type:

Address: NA

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