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Climate + Health Excellence (CHEX) Centers

Burroughs Wellcome Fund

New institutional awards of up to $10,000,000 to stimulate development of strong research, education, and public communications connections between fields that aim to understand and mitigate the impact of climate change on human health. In general, this award will support institutions or consortia that are already moving toward establishing themselves as centers of excellence for understanding climate change’s impact on human health and for leadership in climate education OR public communication around climate and health. Applications from institutions just starting to integrate Climate + Health into their planning are expected to be uncompetitive. Up to three awards will be made over two rounds of competition. Providing support for U.S. and Canadian research and educational Institutions or consortia of research and educational institutions.

GUIDELINES

n Only non-profit research and training institutes in the United States or Canada may submit applications. Consortia may include institutions outside the US or Canada, but only one institution, the institution submitting the proposal, will be paid. Subcontracts are allowed. Research groups working at national laboratories and within the federal government are allowable as partners.

n Institutions should only submit one proposal that reflects the institution’s strategic goals in basic, applied, and implementation research in the area of Climate + Health. Individual departments, centers, etc. within an institution may be part of separate consortium applications—for example, a consortium focusing on shared interests around a region might include participation by several institutions around the region and would not disrupt those institutions own applications as long as there is not significant overlap between the proposals.

n BWF does not provide overhead. Personnel costs, including fringe benefits, are allowed. The administrative costs of running the program are allowable direct costs. Pass-through charges on money sent to other institutions are not allowed. Student tuition is allowed only during the time a student is actively supported by the formal training grant elements proposed.

n For-profit companies and government agencies may not apply, but could be valuable partners.

AI Based Application Success Predictor

🎯 1. Early-Career Focus & Investigator Independence

BWF primarily supports early-stage investigators, notably via the Career Awards for Medical Scientists (CAMS), ideal for physician-scientists transitioning to faculty roles, and the Physician-Scientist Institutional Training Award, aiding fellows into independent researchers .

They also fund postdoc diversity enrichment (PDEP) aimed at under-represented researchers with ≤48 months of postdoc experience .

🏛️ 2. Institutional Eligibility & Support

Eligible institutions include non-profits in the U.S. and Canada (academic, research, or teaching hospitals)—your institution must officially certify your eligibility 

Support letters from mentors and institutional officials are mandatory, especially in fellowship programs 

🧬 3. Scientific & Career Development Goals

BWF looks for projects with innovative, high-impact scientific rigor, especially those addressing neglected areas in biomedical science.

Investigator statements should detail clear career trajectories, demonstrating how funding builds independence and facilitates future advancement .

🧩 4. Strong Mentor and Research Environment

Mentoring is essential—applicants must secure engaged, committed mentors and demonstrate institutional support for protected research time .

Your environment should be rich in appropriate resources, with plans in place to foster your growth.

⏱️ 5. Feasible, Milestone-Oriented Plan

Proposals should include realistic timelines, milestones, and deliverables — e.g., CAMS includes goals for five-year development; PDEP includes training objectives .

Demonstrate how funding serves as a launchpad toward larger investigator-driven grants.

💸 6. Budget Discipline: Direct Costs Only

BWF funding is strictly for direct costs—salaries, supplies, equipment. No indirect costs or travel unless specified 

📑 7. Rigorous Peer Review & Multi-Stage Selection

Most programs require full applications, followed by committee review and, in some cases, interviews (e.g., Innovation in Regulatory Science includes finalist interviews) 

Recruit strong reviewers—BWF values novelty, career potential, and institutional environment.

🌍 8. Commitment to Inclusion and Diversity

BWF encourages applications from historically underrepresented groups, including women, people of color, and individuals from disadvantaged backgrounds .

Reviewers often prioritize geographic and institutional diversity 

🧾 9. Strong Progress Reporting & Accountability

Awardees must submit progress and financial reports, with strict deadlines and oversight (e.g., PRISM reports two months post-completion) .

Regular updates ensure continued funding and readiness for future support.

📋 Summary Table

Predictor	What to Deliver
Early-career/investigator stage	Tailored to CAMS, PDEP, or training grants
Eligible institution	Non-profit U.S./Canada institution certification
Innovative science	High rigor, address neglected research areas
Mentor & environment	Strong, committed mentorship and resources
Milestone-based plan	Feasible timeline & deliverables within funding scope
Direct-cost budget	Salaries, supplies; no indirects/travel
Peer-review readiness	Clear proposal; prepare for LOI, review, interview
Diversity & inclusion	Highlight under-represented status or institutional breadth
Reporting compliance	On-time progress and financial reporting

🛠 Pro Tips for BWF Applications

Start early—assemble mentor letters and institutional sign-off.

Frame your proposal as a career-transforming opportunity.

Highlight novelty and impact, particularly in undervalued areas.

Demonstrate mentorship strength—including structured training plans.

Budget with precision, focusing only on allowable direct costs.

Be prepared for multi-step selection, including potential interviews.

Show your diversity intent, both personal and institutional.

Plan ahead for reporting—maintain clear milestones and tracking.

Specialties

Environmental Health

Eligibility Requirements

n For-profit companies and government agencies may not apply, but could be valuable partners.

Sponsor Details

Sponsor Institute/Organizations: Burroughs Wellcome Fund

Sponsor Type: Corporate/Non-Profit

Address: 21 T.W. Alexander Drive Durham, NC 27713-2847 919-991-5100

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