The Mary Kay Ash Foundation is a non-profit public foundation, which focuses on funding research for innovative grants for translational research of cancers affecting women (ovarian, uterine, breast, endometrial or cervical cancer among others). Translational research is broadly defined as research that will provide a scientific link between laboratory research and the clinic. Ultimately, such research would lead to improvement in diagnosis, prognosis, prevention, or treatment of the cancer. Each year the Foundation extends invitations to NCI designated cancer institutes and accredited medical schools to apply. Only one application is accepted per institution.
Grant proposals are reviewed by a Scientific Research Review Committee comprised of notable members of the American medical and scientific community. Grants are awarded up to $100,000 (combined direct and indirect costs) for a two-year period. The Foundation anticipates funding between 10 and 15 grants annually. Grant submissions are typically open from November through February with a final selection made during the month of June.
In order to receive an invitation, a review by the Research Review Committee Chair and approval by the Foundation Board of Directors will be needed to determine if the inquiring institute is an appropriate fit for the grant program.
Cancer Research Grant Cycle Dates:
Success in this competitive program usually depends on aligning closely with the Foundation’s mission and scientific expectations. Here are the most important predictors:
⭐ 1. Clear Alignment With Foundation Mission
The core mission is to help find cures and improve care for cancers affecting women.
Strong applications clearly articulate impact on women’s health — such as breast cancer, gynecologic cancers, or other malignancies with high prevalence or mortality in women. Mary Kay Ash Foundation
Success Tip: Explicitly frame your research question in terms of women’s cancer outcomes (e.g., survival, early detection, treatment response).
🔬 2. Translational Science Orientation
The Foundation explicitly funds translational research — meaning work that connects laboratory discoveries to clinical or patient-centered outcomes. Mary Kay Ash Foundation
Success Tip:
✔ Define how your project moves beyond basic mechanistic work to clinical or near-clinical implications, whether through biomarkers, therapeutic approaches, or improved prognostic models.
🧪 3. Scientific Innovation and Rigor
Review committees expect well-justified hypotheses and rigorous study design that can realistically be completed within a two-year period. Mary Kay Ash Foundation
Success Tip:
✔ Include clear objectives, compelling preliminary data when possible, and a logical plan showing feasibility within the funding and timeline.
👩⚕️ 4. Investigator Credentials & Environment
Because applications often come from invited top cancer centers, reviewer committees assess whether the PI and team have the right expertise and resources to deliver the project.
Success Tip:
✔ Highlight relevant publications, past impact, clinical collaborations, and institutional support that demonstrate the team’s capability to execute translational research.
📊 5. Potential to Improve Diagnosis, Prognosis or Treatment
Applications that show plausible routes to meaningful change in clinical practice or patient outcomes score well.
Examples include:
Novel biomarkers for early detection
Predictive signatures for treatment response
New therapeutic strategies with preclinical support
Success Tip:
✔ Tie each research aim to a potential measurable clinical benefit.
📅 6. Strategic Institutional Nomination
Since only one application per invited institution is accepted, the internal selection process at your university or cancer center is itself competitive.
Success Tip:
✔ Prepare a compelling internal nomination package (abstract, executive summary, justification) that clearly stands out among institutional priorities.
Before applying:
Confirm whether your institution is invited or eligible to nominate an application this year (internal offices often coordinate this). Vanderbilt University
Clarify internal deadlines and policies since only one proposal goes forward per institution.
During writing:
Emphasize translational endpoints tied to women’s health.
Use clear language to describe the bridge from bench to bedside.
Include realistic milestones aligned with the award’s two-year funding horizon.
🚫 Purely basic science without an explicit translational angle.
🚫 Projects outside cancers that predominantly affect women.
🚫 Multiple institutional proposals — only one is accepted per invited center each year. winshipcancer.emory.edu
| Predictor | Why It Matters |
|---|---|
| Relevance to women’s cancers | Aligns with Mary Kay Ash Foundation’s mission. Mary Kay Ash Foundation |
| Translational focus | Funders emphasize lab-to-clinic impact. Mary Kay Ash Foundation |
| Scientific innovation & rigor | Core to competitive funding decisions. Mary Kay Ash Foundation |
| Investigator and team capability | Suggests feasibility and execution strength. |
| Potential clinical impact | Enhances patient outcomes relevance. |
| Strong internal nomination | Institutional selection is competitive. |
The Mary Kay Ash Foundation is a non-profit public foundation, which focuses on funding research for innovative grants for translational research of cancers affecting women (ovarian, uterine, breast, endometrial or cervical cancer among others). Translational research is broadly defined as research that will provide a scientific link between laboratory research and the clinic. Ultimately, such research would lead to improvement in diagnosis, prognosis, prevention, or treatment of the cancer. Each year the Foundation extends invitations to NCI designated cancer institutes and accredited medical schools to apply. Only one application is accepted per institution.
Eligible Countries:
Sponsor Institute/Organizations: Mary Kay Ash Foundation
Sponsor Type: Corporate/Non-Profit
Address: P.O. Box 799044 Dallas, TX 75379-9044
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Feb 01, 2026
Feb 01, 2026
$100,000
15 awards available.
Affiliation: Mary Kay Ash Foundation
Address: P.O. Box 799044 Dallas, TX 75379-9044
Website URL: https://marykayashfoundation.org/what-we-do/cancer-research/grant-information/
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