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Boosting mental health of young cancer survivors through the European Cancer Patient Digital Centre (ECPDC)

European Commission

Expected Outcome:

Proposals under this topic should aim to deliver results that are directed and tailored towards and contribute to the following expected outcomes:

Through the European Cancer Patient Digital Centre (ECPDC), adolescent and young cancer patients and survivors as well as their caregivers have access to innovative tools and approaches to strengthen their mental health;
Healthcare professionals have access to innovative tools to monitor and support the mental health of cancer patients and survivors as well as their caregivers
Researchers and healthcare professionals have access and use reliable patient reported data to better understand the mental health needs of cancer patients and survivors and provide effective care.

Scope:

As part of its citizens engagement activities, the EU Cancer Mission has launched a dialogue with young cancer survivors, to better understand the specific needs and challenges faced during and after treatment.

Mental health has been systematically highlighted as a major concern, stressing the importance of access to quality psychosocial support including through virtual, digital means along the different stages of the patient’s journey, at diagnosis, during and after treatment.

The communication on a Comprehensive approach to mental health adopted by the European Commission on 7 June 2023[1] calls for the establishment of a platform to boost mental health of young cancer survivors.

In line with this ambition, the overall goal of this topic is to develop an online platform targeting, adolescents, and young adult (AYA) cancer patients and survivors (age 15-39, age of first diagnosis) to address specifically their mental health needs, throughout their journey, at diagnosis, during and after treatment. In particular:

The digital platform should be developed as a module to be fully integrated within the European Cancer Patient Digital Centre whose information portal is currently under development (project EU-CIP[2]). Clear links with EU-CIP should therefore be established and solutions developed to link the two projects, including operational solutions and sustainability.
The platform should include a mix of innovative personalized, evidence-based, and interactive features building on state-of-the-art research to address the mental health needs of AYA patients and survivors[3]. Both cognitive (thinking, reasoning, memory, perceptual etc.), affective (depression, anxiety, etc.), and behaviour change aspects should be considered.
The innovative nature of proposed solutions should be clearly demonstrated.
Multi-device compatibility (mobile, tablet, web) and multilingual support to reach diverse populations should be included.
Specific needs and potential solutions should be discussed and developed in close cooperation with end-users.
Similarly, the efficacy of the proposed solutions to support and boost mental health of young cancer patients, survivors and their caregivers should be demonstrated by testing and validating them by an appropriate number of end users, with different cancer types and belonging to the targeted age group.
Develop, test and integrate in the platform innovative tools for collection and analysis of mental health relevant Patient Reported Outcomes Measures (PROMs) and Patient Reported Experiences Measures (PREMs). Effective mining of lived experience data should be enabled to support for example psychometric development and validation, risk modelling, and the co-creation of personalized psychological measures of mental health.
Therefore tools should be developed and validated in close cooperation with end-users including patients, survivors, healthcare professionals and researchers.
Develop European Health Data Space (EHDS) aligned guidelines to report and deposit relevant patient reported data collected with the above tools.
Projects should include an appropriate mix of stakeholders from various disciplines and sectors, including but not limited to physicians, psychologists, nurses, academia, patients and their caregivers, patient representatives, behavioural scientists, cancer survivorship scientists, AI-experts and solutions providers, SMEs, charities and funding agencies, and research organisations.
Direct involvement of cancer patients and survivors, survivor representative organisations, caregivers is required, along with effective contribution of Social Science and Humanities (SSH) disciplines and the involvement of SSH experts, institutions as well as the inclusion of relevant SSH expertise, in order to produce meaningful and significant results, enhancing the impact of the proposed activities.
Due consideration should be given to initiatives such as: EU-CAYAS-NET[4]; ERN PaedCan[5], Pancare[6] EUonQoL[7], e-Quol[8] and other relevant initiatives, including projects funded under the EU Cancer Mission topic HORIZON-MISS-2024-CANCER-01-05: Improving the understanding and management of late-effects in adolescents and young adults (AYA) with cancer[9].

Successful proposals will be asked to join the 'Quality of life” cluster for the EU Cancer Mission[10] and should include a budget for networking, attendance at meetings, and joint activities[11]. The Commission will facilitate coordination of these activities.

AI Based Application Success Predictor

1️⃣ Strong, Mission-Aligned Impact (Most Important Across EC Calls)

The EC is impact-driven: proposals must show how the project will:

Solve a major European or global societal challenge

Deliver measurable, lasting benefits for EU citizens

Produce outputs that can be used by policymakers, industry, or society

Align with Horizon Europe missions, priorities, and strategic agendas

Predictor: Clear, quantifiable, EU-level impact → strongest scoring factor.

2️⃣ Clear, Ambitious, but Achievable Objectives

Successful proposals show:

2–4 well-defined objectives linked to the Work Programme call text

Clearly articulated research questions or innovation goals

Logical, realistic expected outcomes and deliverables

Feasible scientific and technical approaches

Predictor: Balanced ambition + feasibility.

3️⃣ Excellent, Cutting-Edge Science or Innovation

For RIA/IA/CSA or ERC-level grants, reviewers expect:

High novelty and innovation

Strong grounding in current state-of-the-art

Clear advancement beyond existing approaches

Solid theoretical or experimental foundations

Robust methodological design

Predictor: Scientific excellence is essential for competitive scoring.

4️⃣ Strong Consortium with Complementary Expertise

EC proposals are consortium-driven (except ERC/EIC Accelerator).

High-scoring consortia:

Cover all needed competencies (science, industry, policy, ethics, dissemination)

Include SMEs, industry partners, NGOs, and public bodies when relevant

Are geographically diverse across EU Member States and Associated Countries

Demonstrate strong leadership and communication structures

Predictor: Well-constructed consortium with clear roles.

5️⃣ Clear Pathway From Outputs → Outcomes → Impact

Evaluators look for a credible trajectory showing:

How research leads to specific outputs (data, tools, prototypes)

How outputs lead to uptake or use

How use produces societal, economic, scientific, or policy impact

Strong Key Performance Indicators (KPIs) and impact metrics

Predictor: Clearly mapped impact pathway.

6️⃣ Strong Implementation Plan (Work Packages, Deliverables, Gantt Chart)

Winning proposals have:

Well-designed Work Packages (WPs) with clear scope and responsibilities

Interdependencies identified and risk-mitigation strategies

Detailed milestones and deliverables

Feasible budget aligned with tasks

Strong project management plan

Predictor: High implementation quality boosts the “Excellence” and “Implementation” scores.

7️⃣ Policy Relevance and Contribution to EU Strategies

Especially critical for health, climate, digital, and social calls.

Proposals score higher when they link to:

EU Cancer Mission

EU Green Deal

Digital Europe strategy

EU Biodiversity Strategy

EU Health Union & One Health

Open Science & FAIR data mandates

Predictor: Clear alignment with EU policies.

8️⃣ Strong Stakeholder & Citizen Engagement (Especially in Social & Health Missions)

EC values inclusivity:

Patient groups

Civil society organizations

Public sector bodies

Regulatory agencies

Citizen science components

Stakeholder letters of intent or commitment strengthen credibility.

Predictor: Engagement adds impact and relevance.

9️⃣ Robust Data Management, Open Science, and Ethics

Mandatory components include:

FAIR Data Management Plan

Open access publications

Ethics self-assessment

GDPR compliance

Data security, governance, and ethical approvals

Animal-use reduction and justification (if applicable)

Predictor: Clear compliance with ethical and data obligations.

10️⃣ Well-Justified Budget and Resource Allocation

Budget must be:

Proportional to tasks

Transparent and reasonable

Efficiently distributed among partners

Free from padding or unjustified costs

Predictor: Realistic budgets improve Implementation scores.

🚫 COMMON PITFALLS THAT LEAD TO EC GRANT REJECTION

Pitfall	Why It Fails
Weak connection to Work Programme text	Immediate score reduction
Vague or generic impact statements	Poor Impact score
Overly ambitious, unrealistic scope	Feasibility concerns
Poorly structured consortium	Low Implementation score
No policy relevance	Weak strategic alignment
Lack of concrete KPIs or outcomes	Impact unclear
Weak data or ethics plan	Eligibility/score penalties
No exploitation or dissemination plan	Insufficient impact credibility
Budget misalignment	Reviewer distrust

Specialties

Cancer

Eligibility Requirements

General conditions

1. Admissibility Conditions: Proposal page limit and layout

described in Annex A and Annex E of the Horizon Europe Work Programme General Annexes.

Proposal page limits and layout: described in Part B of the Application Form available in the Submission System.

2. Eligible Countries

described in Annex B of the Work Programme General Annexes.

A number of non-EU/non-Associated Countries that are not automatically eligible for funding have made specific provisions for making funding available for their participants in Horizon Europe projects.

Sponsor Details

Sponsor Institute/Organizations: European Commission

Sponsor Type: Corporate/Non-Profit

Address: Berlaymont Building, Rue de la Loi 200, 1049 Brussels

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