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AGA-R. Robert & Sally Funderburg Research Award in Gastric Cancer

American Gastroenterological Association

Objective

The objective of this AGA Research Foundation award is to support an established investigator in the field of gastric cancer research working to enhance our fundamental understanding of gastric cancer pathobiology or approaches to prevent, treat or cure gastric cancer.

Application requirements

• The proposed research must focus on gastric cancer research. The following areas are of particular interest:
- Gastric mucosal cell biology.
- Regeneration and regulation of cell growth (not as they relate to peptic ulcer disease or repair).
- Inflammation (including Helicobacter pylori) as precancerous lesions.
- Genetics of gastric carcinoma.
- Oncogenes in gastric epithelial malignancies.
- Epidemiology of gastric cancer.
- Etiology of gastric epithelial malignancies.
- Clinical research in the diagnosis or treatment of gastric carcinoma.
- Evidence gaps highlighted in AGA’s GI Cancer Surveillance in Gastric Intestinal Metaplasia guideline including basic, translational and clinical research to inform the evidence base for the guidelines. Clinical research includes health services research to address the implementation of the guidelines into clinical practice.
• A complete research facilities and resources form.
• Biographical sketches for the applicant and all key personnel.
• A list of the applicant’s current and pending other support.
• Upon notification of receipt of this award, the recipient must provide approval from the appropriate institutional committee(s) for use of human subjects or animals. If approval is not necessary, the recipient must provide documentation from the appropriate regulatory committee.
• Recipients must submit scientific and financial progress reports to AGA annually during the award term, and as needed at the request of the AGA Research Foundation. AGA reserves the right to withhold subsequent funding if reporting requirements are not fulfilled.
• Additional information regarding AGA’s pre-award policies is available on the Research Award Policies page.

Budgeting requirements

• Applicants must submit a budget narrative justifying expenses in the budget.
• The following expenses are allowable:
- Salary and benefits of the principal investigator.
- Salary and benefits of research assistants, laboratory technicians or other key personnel.
- Biostatistical support.
- Supplies, animals, equipment and/or other materials necessary for the proposed research.
• The following expenses are not allowed:
- Indirect costs.
- Travel costs.

Award overlap

At the time of application submission, applicants may not hold awards directly related to the proposed research from other organizations (i.e., government agency, foundation, academic institution, professional society, etc.). If the applicant is granted the award and notified of a comparable award from another agency prior to the first payment of this award, the recipient must select one of the two awards (i.e., the recipient may not retain both awards).

Selection criteria

The recipient will be selected based on the following criteria: significance, investigator, innovation, approach, environment, evidence of institutional commitment and relevance to AGA’s mission. Preference is given to applicants proposing novel approaches.

Review process

A selection committee comprising members of the AGA Research Awards Panel will review proposals and select award recipients. Applicants will receive a status notification on or before January 31, 2027, and funding will commence in April 2027.

Application process

The application deadline is September 15, 2026. Applications are only accepted through the AGA Grants Management System. Click the “Apply Now” button to create an account and/or submit an application. Applicants may preview the application as it will appear in the AGA Grants Management System. Please note that this preview is for reference only; all applications are completed online by selecting the “Apply Now” button.

AI Based Application Success Predictor

🧠 1. Strong Focus on Gastroenterology & Hepatology (Non-Negotiable)

Projects must directly address:
- GI or liver diseases
Common areas:
- Inflammatory bowel disease (IBD)
- GI cancers
- Liver disease (NAFLD, cirrhosis)
- Microbiome research

👉 Weak GI relevance → low success probability

🎯 2. Clear Clinical or Patient Impact (Top Predictor)

Successful proposals:

Demonstrate:
- Improvement in diagnosis, treatment, or outcomes
Focus on:
- Patient care
- Disease management
- Prevention

👉 Key question:
“Will this improve care for patients with GI or liver disease?”

🔄 3. Translational Research (Bench → Bedside) (Critical)

Preference for:
- Translational and clinically relevant research
Includes:
- Biomarkers
- Therapeutics
- Clinical trials

👉 Pure basic science is less competitive unless clinically linked

👩‍🔬 4. Early-Career Investigator Development (Major Priority)

Many AGA awards target:
- Fellows and junior faculty

Evaluation includes:

Career trajectory
Independence potential

👉 Strong mentorship is essential

🧪 5. Feasible, Well-Structured Study Design

Must include:
- Clear aims
- Methodology
- Timeline

👉 Overly ambitious or poorly designed studies are frequently rejected

💡 6. Innovation in Key GI Areas

High success rates in:

Microbiome & gut–brain axis
Precision medicine
AI in GI diagnostics
Novel therapeutics

👉 Innovation must be clinically meaningful

🤝 7. Strong Mentorship & Institutional Support

Mentor should:
- Have a strong research track record
Institution must provide:
- Clinical exposure
- Research infrastructure

👉 Mentorship quality significantly impacts outcomes

📊 8. Alignment with AGA Priority Topics

Higher success when aligned with:

Digestive cancers
Chronic liver disease
IBD
Functional GI disorders

👉 Topic alignment improves competitiveness

📈 9. Potential for Future Funding & Publications

AGA funding is often:
- Seed funding for NIH or major grants

👉 Projects that:

Generate preliminary data
Lead to publications
→ score higher

💰 10. Appropriate Scope & Budget

Funding is typically:
- Pilot to mid-scale
Projects must be:
- Focused
- Achievable

👉 Over-scoped proposals are commonly rejected

📊 Summary: Key Predictors (Ranked)

Highest impact factors:

GI/hepatology focus
Clinical impact
Translational relevance

Moderate predictors:
4. Early-career development
5. Feasibility
6. Innovation

Supporting factors:
7. Mentorship
8. Topic alignment
9. Future funding potential

💡 Insider Insight

Compared to NIH:

American Gastroenterological Association is:
👉 clinically focused + career-development oriented
👉 emphasizes pilot and translational research

👉 Key evaluation question:
“Will this project improve GI care and help develop a future investigator?”

✔️ What wins:

Translational GI research
Strong mentorship
Feasible pilot studies

❌ What struggles:

Pure basic science
Weak clinical relevance
Overly ambitious projects

Specialties

Cancer

Oncology

Gastroenterology

Eligibility Requirements

Applicants must be established as an independent investigator in the field of gastric biology.
- MD applicants are considered “established” if seven or more years have elapsed following the completion of clinical training (GI fellowship or its equivalent) at the start date of this award (i.e., April 2027).
- PhD applicants are considered “established” if seven or more years have elapsed following the awarding of the PhD degree and the start date of this award (i.e., April 2027).
• Applicants for this award must hold an MD, PhD and/or equivalent degree (e.g., MBBS, MBChB, DO).
• Applicants must hold a full‐time faculty or equivalent position at an institution in North America (United States, Canada and Mexico).
• AGA membership is required at the time of application submission. Please visit AGA’s membership page or call 301-654-2055 for membership information.
• Applicants performing any type of research (basic, translational, clinical) relevant to gastric cancer are eligible to apply.
• Applicants who are physician-scientists, female or from racial/ethnic groups underrepresented in biomedical research are strongly encouraged to apply.
• AGA Institute Governing Board members are not eligible to apply while they are actively serving on the governing board.

Sponsor Details

Sponsor Institute/Organizations: American Gastroenterological Association

Sponsor Type: Corporate/Non-Profit

Address: 4930 Del Ray Avenue, Bethesda, MD 20814 301-654-2055

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