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AACT Research Award

American Academy of Clinical Toxicology

The goal of this grant program is to provide competitive funding for clinical research that encourages the development of new therapies and treatment and adds to the understanding of the principles and practice of clinical toxicology. The intended research should advance the mission of the AACT to unite "scientists and clinicians in the advancement of research, education, prevention and treatment of diseases caused by chemicals, drugs and toxins." The project may be part of a larger project but must have a specific hypothesis and aims that are separate and distinct.

FUNDING INFORMATION AND APPLICATION DEADLINE

Application deadline: November 1 of every year

One grant, offered every year, of up to $5,000 is available to fund one study. An additional award of a maximum of $1000 will be provided for travel to the NACCT to present the results of the project. Grants are awarded to provide funding for specific projects that address clinical toxicology research and are not intended for long-term support of research programs.

Funds may not be applied to:

Ongoing general operating expenses or existing deficits
Salary support for study personnel
Purchase of equipment, facilities, or software, or other capital costs
Facilities and administrative (institutional indirect) costs

Funding is generally available for:

Consumable supplies and services
Travel to the NACCT meeting to present the results of the proposed project
Subject expenses/reimbursement
Laboratory analysis, statistical analysis and similar activities

AI Based Application Success Predictor

Predictor	Why It Matters	Evidence / AACT Review Focus
Clear clinical relevance to toxicology	Projects must directly relate to clinical poisoning, overdose management, toxic exposures, antidotes, or toxicovigilance. Abstract toxicology or pharmacology topics score poorly.	AACT mission statement & funded project list.
Feasibility within small-scale budget and timeline	AACT funds short-term, pilot, or feasibility studies. Projects requiring large data collection or multicenter infrastructure are unlikely to be funded.	Grant program description: “Pilot projects likely to lead to extramural funding.”
Potential to produce publishable data or future funding	Reviewers prioritize proposals likely to yield tangible results and support future NIH/CDC/DoD applications.	AACT-FTER joint review criteria (2020–2024).
Strong study design and statistical plan	Even small projects must have a rigorous design — clear hypothesis, outcomes, and analysis method.	Review feedback for previous awardees.
Relevance to current toxicology priorities	Topics like opioids, synthetic drugs, envenomation, and emerging toxicants (PFAS, vaping, environmental toxins) are favored.	Recent funded project topics (2021–2024).
Early-career investigator involvement	AACT encourages mentorship and development of trainees. Strong mentor–mentee structure increases success chances.	FTER and Young Investigator program guidelines.
Collaborations with poison centers or hospitals	Projects involving clinical toxicology data networks, poison centers, or real-world case series are prioritized.	Historical grant recipient trends.
Institutional support and resources	Letters confirming access to data, labs, or collaborators strengthen the feasibility argument.	Application instructions.
Concise, well-written proposal	Word limits are strict (usually ≤3 pages). Reviewers reward clarity and precision.	AACT application format.

⚠️ Common Weaknesses in Unsuccessful Applications

Poor fit (e.g., general pharmacology or animal-only toxicology).

Overly ambitious scope for limited budget.

Vague hypotheses or no measurable outcomes.

Weak linkage to clinical application or human relevance.

Lack of mentor support (especially for fellows).

No clear plan for dissemination or next steps.

📊 Patterns from Funded Projects (2015–2024)

Trend / Topic Area	Example or Note
Opioid toxicity and reversal agents	Naloxone distribution, synthetic opioid detection, withdrawal management.
Toxic alcohols and antidote efficacy	Ethylene glycol, fomepizole dosing, ICU outcomes.
Environmental and household exposures	PFAS, lead, pesticide-related hospital admissions.
Novel substances of abuse	Vaping liquids, kratom, synthetic cannabinoids.
Poison center data analysis	Retrospective studies using NPDS or regional databases.
Envenomation or antidote use	Snakebite and scorpion envenomation management.
Education and training research	Simulation-based toxicology teaching innovations.

💡 Top Predictors Summarized

Direct clinical toxicology relevance

Feasible, low-cost project with strong study design

Potential for publication or external funding

Early-career/mentored applicant

Link to poison center or hospital toxicology service

Timely, emerging toxicology issue

Concise, polished proposal within limits

📈 Typical Profile of Successful Applicants

Academic medical center affiliation (MD, PharmD, or PhD).

Early-career or mid-level investigator with toxicology fellowship or poison center role.

Track record of 1–3 publications in Clinical Toxicology or related journals.

Clear mentor support and institutional commitment.

Specialties

Clinical Trials

Others

Eligibility Requirements

The research must focus on clinical toxicology research.
The principal investigator must be a member of the American Academy of Clinical Toxicology in good standing.
Multidisciplinary research teams are encouraged.
The study timeline should not exceed 24 months from project initiation.

Sponsor Details

Sponsor Institute/Organizations: American Academy of Clinical Toxicology

Sponsor Type: Corporate/Non-Profit

Address: 1061 East Main Street, Suite 300 East Dundee, Illinois

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